P
Paul Pévet
Researcher at University of Strasbourg
Publications - 412
Citations - 17661
Paul Pévet is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Melatonin & Circadian rhythm. The author has an hindex of 69, co-authored 410 publications receiving 16754 citations. Previous affiliations of Paul Pévet include Centre national de la recherche scientifique & University of Amsterdam.
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Journal ArticleDOI
MT1 melatonin receptor mRNA expression exhibits a circadian variation in the rat suprachiasmatic nuclei.
TL;DR: The results suggest that only MT1 mRNA can be correlated with 2-iodo-melatonin binding sites in the rat SCN, and the transcriptional regulation of MT1 receptors does not appear to play a role in the daily regulation of melatoninbinding sites availability.
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Phase-shifting effect of 8-OH-DPAT, a 5-HT1A/5-HT7 receptor agonist, on locomotor activity in golden hamster in constant darkness.
TL;DR: 8-OH-DPAT has a chronobiological effect with sensitivity depending upon the circadian time of injection, and a single saline injection is able to induce regular phase-advances at the end of the subjective day (CT10-11).
Journal ArticleDOI
Daily rhythm and regulation of clock gene expression in the rat pineal gland.
Valérie Simonneaux,Vincent-Joseph Poirel,Marie-Laure Garidou,D. Nguyen,E Diaz-Rodriguez,Paul Pévet +5 more
TL;DR: Data show that the expression of Per1 and Cry2 in the rat pineal gland is regulated by the clock-driven changes in norepinephrine, in a similar manner to the melatonin rhythm-generating enzyme arylalkylamine N-acetyltransferase.
Journal ArticleDOI
Tryptophan hydroxylase synthesis is induced by 3',5'-cyclic adenosine monophosphate during circadian rhythm in the rat pineal gland.
TL;DR: The results suggest that the regulation of tryptophan hydroxylase expression by cyclic AMP occurs probably either at the translational level or via transient expression of a transcriptional regulatory element.
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In the rat, exogenous melatonin increases the amplitude of pineal melatonin secretion by a direct action on the circadian clock.
Béatrice Bothorel,Stéphane Barassin,Michel Saboureau,Stéphanie Perreau,Berthe Vivien-Roels,André Malan,Paul Pévet +6 more
TL;DR: The SCN are the target site for the effect of exogenous melatonin on the amplitude of the endogenous melatonin rhythm, with a similar window of sensitivity as its phase‐shifting effect on the pacemaker.