Paul V Beirne

TL;DR: The available evidence is of insufficient quantity and quality to draw any firm conclusions about the effects of self-management education for cystic fibrosis, and there is some limited evidence to suggest that self- management education may improve knowledge in patients with cystic Fibrosis but not in parents or caregivers.

TL;DR: The existing trials provide insufficient evidence to allow confident statements to be made about the relative beneficial and harmful effects of RP and WW for patients with localised prostate cancer, and the results of ongoing trials should help to inform treatment decisions for men with screen-detected localisation prostate cancer.

TL;DR: There is insufficient evidence to advise for or against the use of drug and alcohol testing of occupational drivers for preventing injuries as a sole, effective, long-term solution in the context of workplace culture, peer interaction and other local factors.

TL;DR: Randomised controlled trials evaluating the effects of using hypodermic needles of any gauge or length to administer any type of vaccine to people aged from birth to 24 years found moderate quality evidence from one trial that there is probably little or no difference in immune response.