The invention provides a drug carrier that includes a solid lipid nanoparticle (SLN), wherein the SLN includes tocopherol or a derivative thereof. The invention also provides a pharmaceutical composition that includes a SLN and a biologically active compound, wherein the SLN comprises tocopherol or a derivative thereof. The present invention further provides a colloidal drug delivery system that includes solid lipid nanoparticles (SLNs), wherein the SLNs comprise tocopherol or a derivative thereof. Also provided are methods for preparing the drug carrier, pharmaceutical composition, and colloidal drug delivery system of the invention.

Colloidal solid lipid vehicle for pharmaceutical use

Disclosed herein are topical compositions and methods for using the same to relieve pain in humans, such as pain associated with cancer, bone injuries, old age, and many other forms of pain. Specifically, the present compositions comprise an effective amount of acetone, a salicylate-based compound and an emollient. In addition, the present compositions further comprise one or more compounds including, but not limited to, terpenes and essential oils. The present compositions may be in the form of a liquid (preferably a slightly viscous liquid) or other forms including, but not limited to, salves, creams, gels, ointments or sprays.

Topical compositions and methods for treating pain

The present invention provides a self-emulsifiable composition and a stable topical emulsion comprising same, which comprises salicylate, oils and surfactants and which does not require organic solvents. The invention also provides methods for manufacturing the compositions. The topical compositions of the invention can be used to enhance delivery of salicylates and are useful in the prevention and treatment of pain and inflammation.

Topical composition for delivery of salicylates

The invention is directed to a composition and method in which dried stinging nettle is applied to the skin proximate a pain site to alleviate pain associated with various inflammatory conditions. The characteristic sting of the stinging nettle is absent in the dried nettle of the composition and method.

Application of dried nettle to the skin

New Remedy is all natural remedy for the relief of muscle and joint pain. The mode of application has been basically the same since the beginning of time—using your hands to massage a site with or without something to relieve pain. However, this product is new, and made from what was put on earth for our benefit. It is the combination of herbs and emollients that give the relief when applied.

New remedy: an all natural remedy for the relief of muscle and joints pain

An analgesic liquid liniment composition for topical application to relieve pain, particularly arthritic pain, is formed containing banana peel extracts, alcohol (preferably wintergreen isopropyl alcohol), parsley, acetylsalicylic acid, and pure gum spirits of turpentine. The composition is prepared by forming a mixture of dried bananas with an alcohol, parsley, acetylsalicylic acid and turpentine, aging and then separating the dried banana peels.

Pearline Fowler

Papers

Liquid composition for the topical application to relieve arthritic pain