Showing papers by "Pedro José Sánchez-Soto published in 1998"
TL;DR: In this article, the authors applied chemical analysis, DSC and solubility determinations to the study of solid inclusion complexes of a pesticide, 2,4-dichlorofenoxyacetic acid (2, 4-D) as guest, and β-cyclodextrin (β-CD) as host, in order to produce experimental evidence of the inclusion process and of the stoichiometry of the addition compound.
13 citations
TL;DR: In this paper, the aqueous solubility of 2,4-D was improved by inclusion complexation with α-CD and the formation of such inclusion compounds was studied via the phase-solubility diagram and by DSC and HSM (solid state).
Abstract: The aqueous solubility of the pesticide 2,4-D was improved by inclusion complexation with α-CD. The formation of such inclusion compounds was studied via the phase-solubility diagram (solution state) and by DSC and HSM (solid state). 2,4-D presented a typical Bs Higuchi solubility curve, coprecipitating a 1:2 pesticide-α-CD complex. In order to obtain solid complexes, three processing methods were checked: kneading, coprecipitation and spray-drying. DSC and HSM showed that only the last two of these yielded true inclusion compounds. Chemical analysis also revealed that the stoichiometry of such solid complexes corresponds to a 2,4-D-α-CD ratio of 1:2.
9 citations
TL;DR: In this paper, the extent of the dehydration of three samples of diclofenac/N-(2-hydroxyethyl) pyrrolidine salt (DHEP) obtained from different batches of the preparation from water at industrial level was investigated.
8 citations