A 15-year study of osseointegrated implants in the treatment of the edentulous jaw

Criteria for the evaluation of dental implant success are proposed These criteria are applied in an assessment of the long-term efficacy of currently used dental implants including the subperiosteal implant, the vitreous carbon implant, the blade-vent implant, the single-crystal sapphire implant, the Tubingen implant, the TCP-implant, the TPS-screw, the ITI hollow-cylinder implant, the IMZ dental implant, the Core-Vent titanium alloy implant, the transosteal mandibular staple bone plate, and the Branemark osseointegrated titanium implant An attempt has been made to standardize the basis for comments on each type of implant

https://coimplante.odo.br/Biblioteca/Trabalhos%20classicos/A%20review%20and%20proposed%20a%20criteria%20of%20success%20-%20Albrektson%20et%20al.pdf

The long-term efficacy of currently used dental implants: a review and proposed criteria of success.

A total of 2895 threaded, cylindrical titanium implants have been inserted into the mandible or the maxilla and 124 similar implants have been installed in the tibial, temporal or iliac bones in man for various bone restorative procedures. The titanium screws were implanted without the use of cement, using a meticulous technique aiming at osseointegration-a direct contact between living bone and implant. Thirty-eight stable and integrated screws were removed for various reasons from 18 patients. The interface zone between bone and implant was investigated using X-rays, SEM, TEM and histology. The SEM study showed a very close spatial relationship between titanium and bone. The pattern of the anchorage of collagen filaments to titanium appeared to be similar to that of Sharpey's fibres to bone. No wear products were seen in the bone or soft tissues in spite of implant loading times up to 90 months. The soft tissues were also closely adhered to the titanium implant, thereby forming a biological seal, preven...

https://www.tandfonline.com/doi/pdf/10.3109/17453678108991776

Osseointegrated Titanium Implants: Requirements for Ensuring a Long-Lasting, Direct Bone-to-Implant Anchorage in Man

Surface treatments of titanium dental implants for rapid osseointegration

Biomaterials are being used with increasing frequency for tissue substitution. Complex devices such as total joint replacements and the total artificial heart represent combinations of polymers and metal alloys for system and organ replacement. The major barriers to the extended use of these devices are the possibility of bacterial adhesion to biomaterials, which causes biomaterial-centered infection, and the lack of successful tissue integration or compatibility with biomaterial surfaces. Interactions of biomaterials with bacteria and tissue cells are directed not only by specific receptors and outer membrane molecules on the cell surface, but also by the atomic geometry and electronic state of the biomaterial surface. An understanding of these mechanisms is important to all fields of medicine and is derived from and relevant to studies in microbiology, biochemistry, and physics. Modifications to biomaterial surfaces at an atomic level will allow the programming of cell-to-substratum events, thereby diminishing infection by enhancing tissue compatibility or integration, or by directly inhibiting bacterial adhesion.

https://science.sciencemag.org/content/sci/237/4822/1588.full.pdf

Biomaterial-centered infection: microbial adhesion versus tissue integration.

Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scand

3,855,638 12/1974 Pilliar .............................................. 3/1 4,145,764 3/1979 Suzuki et al. ................................ 3/19 4,195,409 4/1980 Child ............. ... 433/175 4,547,157 10/1985 Driskell. ... 433/173 4,722,688 2/1988 Lonca ........ ... 433/173 4,818,559 4/1989 Hama et al. .............................. 623/11 4,826,434 5/1989 Krueger ........ 433/174 4,874,434 10/1989 Riggs, Jr. ...... ... 134/3 4,908,030 3/1990 Linkow et al. ... ... 623/16 4,911,953 3/1990 Hosonuma et al. .. ... 427/224 4,944,754 7/1990 Linkow et al. ........................... 623/16 5,000,685 3/1991 Brajnovic .......... ... 433/173 5,030,096 7/1991 Hurson et al. ... 433/173 5,071,351 12/1991 Green et al. .............................. 422/23 5,188,800 2/1993 Green et al. ............................ 433/173

Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period.

This study reviews the long-term outcome of prostheses and fixtures (implants) in 759 totally edentulous jaws of 700 patients. A total of 4,636 standard fixtures were placed and followed according to the osseointegration method for a maximum of 24 years by the original team at the University of Goteborg. Standardized annual clinical and radiographic examinations were conducted as far as possible. A lifetable approach was applied for statistical analysis. Sufficient numbers of fixtures and prostheses for a detailed statistical analysis were present for observation times up to 15 years. More than 95% of maxillae had continuous prosthesis stability at 5 and 10 years, and at least 92% at 15 years. The figure for mandibles was 99% at all time intervals. Calculated from the time of fixture placement, the estimated survival rates for individual fixtures in the maxilla were 84%, 89%, and 92% at 5 years; 81% and 82% at 10 years; and 78% at 15 years. In the mandible they were 91%, 98%, and 99% at 5 years; 89% and 98% at 10 years; and 86% at 15 years. (The different percentages at 5 and 10 years refer to results for different routine groups of fixtures with 5 to 10, 10 to 15, and 1 to 5 years of observation time, respectively.) The results of this study concur with multicenter and earlier results for the osseointegration method.

Per-Ingvar Brånemark

Papers

A 15-year study of osseointegrated implants in the treatment of the edentulous jaw

Osseointegrated Titanium Implants: Requirements for Ensuring a Long-Lasting, Direct Bone-to-Implant Anchorage in Man

Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scand

Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period.

Long-term follow-up study of osseointegrated implants in the treatment of totally edentulous jaws.