Peter G. Scheffer

TL;DR: It is found that oxidative stress, as measured by 8-OHdG and F2-isoprostanes, is increased in depression, and larger-scale studies are needed to extend the evidence on oxidative stress in depression.

TL;DR: Increasing evidence suggests that MPO is causally linked to atherosclerosis and its measurement may improve CVD risk estimation, and before MPO can be used in routine clinical practice, standardization of sampling and laboratory procedures is needed.

TL;DR: This study shows for the first time in an in vivo model of diabetes that GLO-I overexpression reduces hyperglycemia-induced levels of carbonyl stress, AGEs, and oxidative stress.

TL;DR: The lower lyso-PC/PC ratio in CSF of patients with AD may reflect alterations in the metabolism of choline-containing phospholipids in the brain in AD, and suggests that PC species containing linoleic acid or arachidonic acid are equally involved.

TL;DR: In healthy males, after two consecutive fat‐rich meals, mild elevations in plasma glucose and triacylglycerol were paralleled by impaired FMD, increased markers of oxidative stress and circulating MPs, in particular, after the second meal, which may have consequences for subjects with postprandial dysmetabolism, including those with Type 2 diabetes.