P
Philip D. Magnus
Researcher at University of Texas System
Publications - 12
Citations - 56
Philip D. Magnus is an academic researcher from University of Texas System. The author has contributed to research in topics: Phenylsilane & Yield (chemistry). The author has an hindex of 4, co-authored 12 publications receiving 56 citations.
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Patent
Short synthetic route to taxol and taxol derivatives
TL;DR: A short route to the total synthesis of the core skeleton of the taxol ring system is described in this paper, where the same sequence of transformations can be carried out to make the 7-hydroxy series, and connect the additional carbon atoms required for the A-ring.
Patent
Conversion of alpha,beta-unsaturated ketones and alpha,beta-unsaturated esters into alpha-hydroxy ketones and alpha-hydroxy esters using Mn(III) catalyst, phenylsilane and dioxygen
Philip D. Magnus,Andrew H. Payne +1 more
TL;DR: In this article, a single step process for the conversion of α,β-unsaturated ketones was proposed, which operates at neutral reaction conditions that prevent the formation of side reactions and gives a yield approximately 30% higher than the currently used processes.
Patent
Synthesis of tetrahydroquinoline enediyne core analogs of dynemicin
TL;DR: In this article, a process for the preparation of the core azobicyclo[7.3.1]tridecaenediyne moiety of the antitumor antibiotic dynemicin is described.
Patent
Synthesis of morphine and related derivatives
TL;DR: In this paper, the authors present methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof, wherein the starting compound is biphenyl, and their present invention relates to methods for synthesizing Galanthamine and morphine.
Patent
Synthesis of navelbine analogs
Philip D. Magnus,Lee S. Thurston +1 more
TL;DR: In this article, a de novo synthesis of the norcatharanthine moiety of navelbine is presented, which includes condensing a Grignard reagent prepared from an amine-protected R(+)-piperidinyl methanol with an N-protected 2-methoxyoxalyl indole.