Philip J. Johnson

TL;DR: It is now more clearly understood that EMS is related to abnormal glucose metabolism and insulin resistance, rather than the previously held belief that these symptoms were consistent with hypothyroid activity which developed as a horse ages.

TL;DR: In this article, the relationship between obesity, insulin insensitivity, and laminitis in horses has been investigated, and it has been hypothesized that obesity-associated Laminitis arises as a consequence of vascular changes and a hypercoagulable state similar to the development of atherosclerosis in human type 2 diabetes.

TL;DR: Analysis of connective tissue obtained from the hoof of six laminitic and eight non-laminitic adult horses showed that collagenolytic activities corresponding to the 92 kDa, 72 kDa and 66 kDa bands were induced in the laminationitic tissues.

TL;DR: The use of 5 common DNA extraction methods on fecal samples from 5 different species are investigated to show that the method of DNA extraction impacts DNA concentration and purity, successful NGS amplification, and influences microbial communities seen in NGS output dependent on the species of fecal sample and the DNA extraction method used.

TL;DR: There was a notable difference in the temporal pattern of inflammatory events between the BWE and CHO models, with the majority of laminar inflammatory events appearing to occur at or near the onset of lameness in the CHO model, whereas many of these events peak earlier in the developmental stages in the B THE AUTHORS model.