P
Pingjun Zhu
Researcher at Chinese PLA General Hospital
Publications - 5
Citations - 823
Pingjun Zhu is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Unfolded protein response & Medical history. The author has an hindex of 3, co-authored 5 publications receiving 610 citations.
Papers
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Journal ArticleDOI
Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study.
Yingzhen Du,Lei Tu,Pingjun Zhu,Mi Mu,Runsheng Wang,Pengcheng Yang,Xi Wang,Chao Hu,Rongyu Ping,Peng Hu,Tianzhi Li,Feng Cao,Christopher Chang,Qinyong Hu,Yang Jin,Guogang Xu +15 more
TL;DR: In this depictive study of 85 fatal cases of COVID-19, most cases were males aged over 50 years with noncommunicable chronic diseases, and the majority of the patients died of multiple organ failure.
Journal ArticleDOI
Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: A Retrospective Observational Study
Yingzhen Du,Lei Tu,Pingjun Zhu,Mi Mu,Runsheng Wang,Pengcheng Yang,Xi Wang,Chao Hu,Rongyu Ping,Peng Hu,Tianzhi Li,Feng Cao,Qinyong Hu,Yang Jin,Guogang Xu +14 more
Journal ArticleDOI
Pirfenidone alleviates lipopolysaccharide-induced lung injury by accentuating BAP31 regulation of ER stress and mitochondrial injury.
Yingzhen Du,Pingjun Zhu,Xi Wang,Mi Mu,Hongxia Li,Yan-Hong Gao,Xuebing Qin,Yan Wang,Zhijian Zhang,Geping Qu,Guogang Xu,Christopher Chang,Christopher Chang,Tianzhi Li,Xiangqun Fang,Sen-Yang Yu +15 more
TL;DR: The beneficial effect of pirfenidone on ER stress and mitochondrial dysfunction mediated apoptosis via upregulation of BAP31 is confirmed and may be considered as a potential agent for the treatment of ALI in the future.
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RIPK3 Induces Cardiomyocyte Necroptosis via Inhibition of AMPK-Parkin-Mitophagy in Cardiac Remodelling after Myocardial Infarction.
Pingjun Zhu,Kun Wan,Ming Yin,Peng Hu,Yifan Que,Xin Zhou,Lei Zhang,Tianzhi Li,Yingzhen Du,Guogang Xu,Xiangqun Fang +10 more
TL;DR: In this article, the authors showed that RIPK3 expression was upregulated in myocardial tissue after MI in a mouse model by coronary artery ligation, as well as in the cardiomyocytes following hypoxic injury in vitro.
Journal ArticleDOI
Reply to Tsolaki and Zakynthinos: Are Patients with COVID-19 Dying of or with Cardiac Injury?
TL;DR: In a recent report involving 416 hospitalized patients from Wuhan, 19.7% presented with “acute myocardial injury”, and 13 patients (16%) died from cardiac problems, namely cardiac arrest, acute coronary syndrome (ACS), and malignant arrhythmia.