Placido Gitto

TL;DR: It is concluded that treatment with melatonin might result in a wide range of health benefits, improved quality of life and reduced healthcare costs and may help reduce complications in the neonatal period.

TL;DR: Evidence continues to accumulate that oxidative stress is a mediator of endothelial dysfunction and thus contributes to the cardiovascular complications of preeclampsia and may play a role in the pathogenesis of a number of diseases in the newborn.

TL;DR: The results indicate that the melatonin may be beneficial in the treatment of newborn infants with asphyxia, and the protective actions of melatonin in this study may relate to the antioxidant properties of the indole as well as to the ability ofmelatonin to increase the efficiency of mitochondrial electron transport.

TL;DR: Following melatonin administration, nitrite/nitrate levels decreased significantly, whereas they remained high and increased further in the respiratory distress syndrome infants not given melatonin.

TL;DR: Improved survival because of advances in neonatal care has resulted in an increased number of infants at risk for chronic lung disease, and melatonin treatment reduced the proinflammatory cytokines and improved the clinical outcome.