P
Pradeep B. Lasonkar
Researcher at National Chemical Laboratory
Publications - 14
Citations - 92
Pradeep B. Lasonkar is an academic researcher from National Chemical Laboratory. The author has contributed to research in topics: Duff reaction & Enantioselective synthesis. The author has an hindex of 6, co-authored 13 publications receiving 70 citations. Previous affiliations of Pradeep B. Lasonkar include Council of Scientific and Industrial Research & University of Mississippi.
Papers
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Journal ArticleDOI
Scrutiny of Novel Tosylacrylimidamide as Non‐Classical Bioisosteres of Sulfonylurea in Type II Diabetes Mellitus through Synthesis, In Vitro and Docking Studies
Santosh Kumar Surve,Rutikesh Gurav,A M. Gurav,Pradeep B. Lasonkar,Jeevan M. Kondre,Veerabhadra Kalalawe,Sunita Salunke Gawali,Shankar Poshetti Hangirgekar +7 more
TL;DR: In this article , the ability of tosylacrylimidamide to stimulate insulin secretion from MIN-6 cells was investigated, the results indicated that compound 4 e, 4 f, 4 g were the most effective insulin secretagogue's amongst reported, then 4 e and 4 f were further evaluated at various concentration of compound keeping glucose concentration constant (5 mM).
Patent
A process for the synthesis of olopatadine
TL;DR: In this paper, a process for the synthesis of olopatadine is described, and a process that results in an improved yield of the desired Z isomer is presented.
Journal ArticleDOI
A Novel and Enantioselective Synthesis of D-(+)-Biotin via a Sharpless Asymmetric Dihydroxylation Strategy.
TL;DR: In this paper, the Sharpless dihydroxylation of the α,β-unsaturated ester (I) was used for asymmetric synthesis of the olefin (III), a known synthetic precursor of (+)-biotin.
Journal ArticleDOI
One-Pot Migration—Formylation of Benzyl Aryl Ethers under Duff Reaction Condition.
TL;DR: In this article, a one-pot migration-formylation of benzyl aryl ethers under the Duff reaction condition is described, and the reaction was performed with HMTA (hexamethylene tetramine) and TFA (trifluoroacetic acid).