P
Prakash Muthudoss
Researcher at Center for Global Development
Publications - 10
Citations - 60
Prakash Muthudoss is an academic researcher from Center for Global Development. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 6 publications receiving 33 citations. Previous affiliations of Prakash Muthudoss include Dr. Reddy's Laboratories.
Papers
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Journal ArticleDOI
Iso-Structurality Induced Solid Phase Transformations: A Case Study with Lenalidomide
Ramanaiah Chennuru,Ramanaiah Chennuru,Prakash Muthudoss,Raja Sekhar Voguri,Srividya Ramakrishnan,Peddy Vishweshwar,R. Ravi Chandra Babu,Sudarshan Mahapatra +7 more
TL;DR: In this article, a comprehensive polymorph screening was performed on five forms of lenalidomide (LDM): Form-3 (DMF-solvate), Form-4 (anhydrous) and Form-5 (DMSO solvate).
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Micronization and Agglomeration: Understanding the Impact of API Particle Properties on Dissolution and Permeability Using Solid State and Biopharmaceutical “Toolbox”
TL;DR: In this paper, the effect of agglomeration on micronized model active pharmaceutical ingredient (API) was investigated and the influence of API agglerate strength on dissolution and permeation was unraveled.
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Preliminary studies on unusual polymorphs of thymine: Structural comparison with other nucleobases
Ramanaiah Chennuru,Ramanaiah Chennuru,Prakash Muthudoss,Srividya Ramakrishnan,Amjad Basha Mohammad,R. Ravi Chandra Babu,Sudarshan Mahapatra,Susanta K. Nayak +7 more
TL;DR: Two polymorphs of anhydrous thymine, Form-R2 and FormR4, were obtained via sublimation crystallization and desolvation technique respectively as discussed by the authors.
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Quantitative Microscopy: Particle Size/Shape Characterization, Addressing Common Errors Using 'Analytics Continuum' Approach.
TL;DR: The developed methodology can be utilized as a quantitative procedure to assesses the suitability of API/excipients from different batches or from alternate vendors and can significantly help in understanding the differences between material even on a minor scale.
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In-Situ Metastable Form : A Route For The Generation Of Hydrate And Anhydrous Forms Of Ceritinib
Ramanaiah Chennuru,Ramanaiah Chennuru,Ravi Teja Koya,Pavan Kommavarapu,Saladi Venkata Narasayya,Prakash Muthudoss,Peddy Vishweshwar,R. Ravi Chandra Babu,Sudarshan Mahapatra +8 more
TL;DR: In this paper, the crystal structure and insight into any solid form of ceritinib are not available in the literature, and novel polymorph identification is chosen as one of the challenging paths to address the issue.