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Q

Qiang Li

Researcher at University of Alberta

Publications -  27
Citations -  1505

Qiang Li is an academic researcher from University of Alberta. The author has contributed to research in topics: Polycystin 2 & Ion channel. The author has an hindex of 20, co-authored 25 publications receiving 1389 citations.

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Detecting protein-protein interactions by Far western blotting.

TL;DR: Far western blotting (WB) was derived from the standard WB method to detect protein–protein interactions in vitro and allows prey proteins to be endogenously expressed without purification.
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Alpha-actinin associates with polycystin-2 and regulates its channel activity

TL;DR: It is discovered that both intracellular N- and C-termini of PC2 associate with alpha-actinins, actin-binding and actin -bundling proteins important in cytoskeleton organization, cell adhesion, proliferation and migration.
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Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine

TL;DR: The unusual substrate specificity and close sequence identity with GLUT5 suggest that GLUT7 represents an intermediate between class II GLUTs and the class I member GLUT2, and comparison between these proteins may provide key information as to the structural determinants for the recognition of fructose as a substrate.
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Direct binding of α-actinin enhances TRPP3 channel activity

TL;DR: Physical and functional interactions between TRPP3 and α‐actinin, an actin‐bundling protein known to regulate several types of ion channels, are investigated, finding that α‐actsinin not only attaches TR PP3 to the cytoskeleton but also up‐regulates TRPP 3 channel function.