Qing Wang

TL;DR: A novel, high sensitive, and specific DNA assay based on gold nanoparticle (AuNP) colorimetric detection and hybridization chain reaction (HCR) amplification has been demonstrated and offers high selectivity for the determination between perfectly matched target oligonucleotides and targets with single base-pair mismatches.

TL;DR: A sensitive aptasensor was demonstrated for exosomes detection by surface plasmon resonance (SPR) with dual gold nanoparticle (AuNP)-assisted signal amplification that showed a 104-fold improvement in LOD compared to commercial ELISA.

TL;DR: This sensitive and versatile surface plasmon resonance (SPR) biosensor was used for cancer cell detection coupled with the cell-specific aptamer modified magnetic nanoparticles and showed high selectivity toward single-base mismatch.

TL;DR: A simple and sensitive surface plasmon resonance (SPR) biosensor for miRNA detection was developed using graphene oxide-gold nanoparticles (GO-AuNPs) hybrids as signal amplification element with excellent ability to discriminate differences among miRNA-200 family members.

TL;DR: High affinity DNA aptamers against C-reactive protein were obtained using a microfluidic chip and used for the construction of an Au nanoparticle enhanced surface plasmon resonance biosensor, which was introduced for the detection of CRP.