Q
Qun-Yan Xiang
Researcher at Central South University
Publications - 3
Citations - 104
Qun-Yan Xiang is an academic researcher from Central South University. The author has contributed to research in topics: Vascular smooth muscle & Calcification. The author has an hindex of 1, co-authored 3 publications receiving 2 citations.
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Journal ArticleDOI
Roles and mechanisms of exosomal non-coding RNAs in human health and diseases.
Chen Li,Yu-Qing Ni,Hui Xu,Qun-Yan Xiang,Yan Zhao,Jun-Kun Zhan,Jie-Yu He,Shuang Li,You-Shuo Liu +8 more
TL;DR: In this paper, the authors comprehensively discuss the underlying regulatory mechanisms of exosomes in human diseases, including cancers, metabolic diseases, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases and infectious diseases, to determine their potential implication in biomarker identification and therapeutic exploration.
Journal ArticleDOI
LncRNA‐ES3 inhibition by Bhlhe40 is involved in high glucose–induced calcification/senescence of vascular smooth muscle cells
Jia-Yu Zhong,Xing-Jun Cui,Jun-Kun Zhan,Yan-Jiao Wang,Shuang Li,Xiao Lin,Qun-Yan Xiang,Yu-Qing Ni,Le Liu,You-Shuo Liu +9 more
TL;DR: The results demonstrate that lncRNA‐ES3 triggers gene silencing of multiple miRNAs by binding to Bhlhe40, leading to calcification/senescence of VSMCs, and suggest that pharmacological interventions targeting lncRNAs may be therapeutically beneficial in ameliorating vascular calcifying/aging.
Posted ContentDOI
Exosomal MFGE8 from high glucose induced endothelial cells is involved in calcification/senescence of vascular smooth muscle cells
Yu-Qing Ni,Shuang Li,Xiao Lin,Yan-Jiao Wang,Jie-Yu He,Wanling Song,Qun-Yan Xiang,Yan Zhao,Chen Li,Yi Wang,Hua-Hua Li,Zhen Liang,Jun-Kun Zhan,You-Shuo Liu +13 more
TL;DR: In this article, milk fat globule epidermal growth factor 8 (MFGE8) was enriched in high glucose induced human umbilical vein endothelial cell exosomes (HG-HUVEC-Exo) and regulate vascular smooth muscle cells (VSMCs) induced by hyperglycemia.