The safety of quinolones--a meta-analysis of pregnancy outcomes.

Urinary tract infections (UTIs) are a common complication of pregnancy. Symptomatic UTI occurs in 1% to 2% of pregnancies, while asymptomatic bacteriuria has been reported in 2% to 13% of pregnant women.1 Several anatomical and hormonal changes in pregnant women lead to ureteral dilatation and urinary stasis,2 which contribute to the increased risk of developing UTIs. Untreated UTIs can lead to complications, such as pyelonephritis, low-birth-weight infants, premature delivery, and, occasionally, stillbirth3; therefore, prompt treatment of symptomatic UTIs and asymptomatic bacteriuria is warranted in pregnant women.

https://www.cfp.ca/content/cfp/54/6/853.full.pdf

Urinary tract infections in pregnancy

https://www.derm.theclinics.com/article/S0733-8635(06)00002-7/pdf

The use of dermatologic drugs in pregnancy and lactation

Pregnancy outcomes following quinolone and fluoroquinolone exposure during pregnancy: A systematic review and meta-analysis.

QUESTION After hearing about outbreaks of illness resulting from Listeria and Salmonella, many of my patients are wondering about the risks of food-borne illnesses during pregnancy and what they can do to reduce their chances of contracting them.

ANSWER Although heating or cooking food is the best way to inactivate food-borne pathogens, improved standards and surveillance have reduced the prevalence of contaminated foods at grocery stores. Therefore, it is no longer necessary for pregnant women to avoid foods like deli meats and soft cheeses (associated with Listeria); soft-cooked eggs (associated with Salmonella); or sushi and sashimi. Regardless of whether seafood is raw or cooked, pregnant women should choose low mercury seafood (eg, salmon and shrimp) over higher mercury varieties (eg, fresh tuna). Pregnant women should ensure that their food is obtained from reputable establishments; stored, handled, and cooked properly; and consumed within a couple of days of purchasing.

https://www.cfp.ca/content/cfp/56/4/341.full.pdf

R Andreou

Papers

New postmarketing surveillance data supports a lack of association between quinolone use in pregnancy and fetal and neonatal complications