R
R. J. Schaur
Researcher at University of Graz
Publications - 32
Citations - 7379
R. J. Schaur is an academic researcher from University of Graz. The author has contributed to research in topics: Lipid peroxidation & 4-Hydroxynonenal. The author has an hindex of 16, co-authored 32 publications receiving 7098 citations.
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Journal ArticleDOI
Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electrospray MS
Corinne M. Spickett,N Rennie,H Winter,Laura Zambonin,Laura Landi,A. Jerlich,R. J. Schaur,Andrew R. Pitt +7 more
TL;DR: This is the first report of direct detection by LC-MS of intact oxidized phospholipids induced in cultured cells subjected to oxidative stress.
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4-Hydroxynonenal modifies the effects of serum growth factors on the expression of the c-fos proto-oncogene and the proliferation of HeLa carcinoma cells.
TL;DR: In both cases HNE possibly interferes with the signal transduction pathway, which is initiated by external growth factors, and the increased c-fos expression might be part of an abortive attempt to overcome the stressful condition raised by a cytotoxic concentration of HNE.
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The inhibitory effect of 4-hydroxy-nonenal on DNA-polymerases alpha and beta from rat liver and rapidly dividing Yoshida ascites hepatoma.
TL;DR: Whether the reaction catalysed by DNA polymerase is the most sensitive step of the DNA replicase system of native cells is investigated.
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Detection of 4-hydroxynonenal as a product of lipid peroxidation in native Ehrlich ascites tumor cells.
Paul Winkler,Wolfgang Lindner,Hermann Esterbauer,Erwin Schauenstein,R. J. Schaur,G. A. Khoschsorur +5 more
TL;DR: The results confirm the expectation by Schauenstein and Esterbauer that endogenous lipid peroxidation gives rise to a distinct intracellular level of alpha, beta-unsaturated aldehydes.
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Oxidative burst and anticancer activities of rat neutrophils
Morana Zivkovic,Marija Poljak-Blazi,G. Egger,Suzana Borović Šunjić,R. J. Schaur,Neven Zarkovic +5 more
TL;DR: The results confirm that in the case of rapidly growing tumors such as murine W256 carcinoma neutrophils have antitumorous effects in the early phase of tumor development.