A kinetic method for the determination of thiourea by its catalytic effect in micellar media.

N-bromosuccinimide as a direct titrant for thiourea and thioacetamide using bordeaux red as an indicator

In the present method Isoniazid (INH) has been determined volumetrically using N-bromosuccinimide. INH was taken in aqueous medium and titrated against standard N-bromosuccinimide using Bordeaux Red as indicator. the end point was taken as distinct yellow. the relative standard deviation was 1.5% when 0.5 mg INH was analysed. A number of pharmaceutical preparations were also taken and their INH contents were determined both by this as well as standard method. It was observed that NBS method was more convenient, accurate, precise and rapid.

Determination of isonicotinic acid hydrazide using N-bromosuccinimide

The harmful and destructive effects of excessive consumption of thiourea in various industries and agriculture have caused health and environmental concerns. Hence, attention has been paid to the need for analysis and detection thiourea at very low concentrations. The aim of this study was to determine the efficiency of electrochemical sensor based on glass carbon electrode modified with Ag nanoparticles and alizarin yellow to detect thiourea as a pollutant. Glass carbon electrode was first modified by alizarin yellow polymer and Ag nanoparticles through electropolymerization and chronoamperometry methods, respectively. The characteristics of the modified electrode were determined through FESEM and EDAX analysis and thiourea concentration was measured through cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. The results showed that the linear range, limit of detection, and sensitivity were 10 to 940 µM, 3.3 µM and 0.181 µA/µM, respectively. The stability and reproducibility of the sensor response as well as the interference effect of some anion species were investigated on the performance of the sensor in determining thiourea. The results indicate the optimum stability and reproducibility and no interference effect of the studied species on efficiency of the sensor in determining thiourea.

Fabrication of a sensitive electrochemical sensor based on Ag nanoparticles and alizarin yellow polymer: Application to the detection of an environmental pollutant thiourea

A rapid and convenient method for the determination of sulfur amino acids is described. N-Bromosuccinimide is used as a direct titrant using Bordeaux Red as an indicator. The red color of the indicator changes to distinct yellow with a sharp end point. The error is less than ±0.5% in most cases, and in a few cases it is near ±1%. Comparison of three methods has been made: back-titration; direct method using either Crystal Violet or Bordeaux Red as indicators. Bordeaux Red proved to be the more suitable end point indicator. Aqueous solutions of N-bromosuccinimide are stable over a period of several days when kept refrigerated and protected from light.

Microdetermination of sulfur amino acids with N-bromosuccinimide using bordeaux red as an indicator

A titrimetric procedure is described for the determination of thiourea and thioacetamide. N-Bromosuccinimide is used to quantitatively oxidize the sulfur in these molecules to sulfate, the extent of reaction being monitored iodometrically. From –15 mg. of thiourea and thioacetamide were analyzed with an average standard deviation of about 0.05 mg.

R. J. Thibert

Papers

Titrimetric Determination of Thiourea and Thioacetamide Using N-Bromosuccinimide