R
R. L. Kassel
Publications - 2
Citations - 4532
R. L. Kassel is an academic researcher. The author has contributed to research in topics: Tumor necrosis factor alpha & Necrosis. The author has an hindex of 2, co-authored 2 publications receiving 4395 citations.
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Journal ArticleDOI
An endotoxin-induced serum factor that causes necrosis of tumors
TL;DR: It is proposed that TNF mediates endotoxin-induced tumor necrosis, and that it may be responsible for the suppression of transformed cells by activated macrophages.
Book ChapterDOI
Endotoxin-induced tumor necrosis factor.
Herbert F. Oettgen,Elizabeth A. Carswell,R. L. Kassel,N. Fiore,Barbara Williamson,Michael K. Hoffmann,K. Haranaka,Lloyd J. Old +7 more
TL;DR: The serum of BCG-infected mice treated with endotoxin contains a substance (tumor necrosis factor, TNF) which mimics the tumor-necrotizing action of endotoxin itself, and has striking effects on immunologic reactions in vitro.