R
R. L. Verwilghen
Researcher at Katholieke Universiteit Leuven
Publications - 42
Citations - 1781
R. L. Verwilghen is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Bone marrow & Leukemia. The author has an hindex of 23, co-authored 42 publications receiving 1769 citations.
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Journal ArticleDOI
Prognostic factors in the myelodysplastic syndromes: importance of initial data on peripheral blood counts, bone marrow cytology, trephine biopsy and chromosomal analysis.
G. Tricot,Robert Vlietinck,Marc Boogaerts,B. Hendrickx,C De Wolf-Peeters,H. Van den Berghe,R. L. Verwilghen +6 more
TL;DR: An analysis of clinical, haematological, histological and cytogenetic data was performed in 85 consecutive patients with myelodysplastic syndromes, finding that patients with refractory anaemia and AISA had a lower incidence of evolution to AML, but a higher mortality rate from infections and/or bleeding.
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Bone marrow histology in myelodysplastic syndromes. II. Prognostic value of abnormal localization of immature precursors in MDS.
TL;DR: It is concluded that bone marrow biopsy provides useful information for the prognosis of MDS and that the presence of ALIP has greater predictive value than the more commonly used parameters deduced from cytology and karyotype.
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The myelodysplastic syndromes: different evolution patterns based on sequential morphological and cytogenetic investigations.
TL;DR: Serial morphological and cytogenetic investigations were performed in 46 patients with the myelodysplastic syndrome and Twenty‐one patients (45.5%) progressed to AML.
Journal ArticleDOI
A new chromosome anomaly in acute lymphoblastic leukemia (ALL).
H. Van den Berghe,G. David,A. Broeckaert-Van Orshoven,Andries Louwagie,R. L. Verwilghen,M Casteels-Van Daele,Ephrem Eggermont,Roger Eeckels +7 more
TL;DR: A new chromosome anomaly in acute lymphoblastic leukemia is reported, characterized by a (4;11)(q13;q22) reciprocal translocation, which appears to be more characteristic of ALL than of congenital leukemia.
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Bone marrow histology in myelodysplastic syndromes. I. Histological findings in myelodysplastic syndromes and comparison with bone marrow smears.
TL;DR: The bone‐marrow biopsy has a role in difficult cases, where the diagnosis of MDS can not be established on just bone marrow smears, and features of abnormal erythropoiesis and myelopoies is more easily detected in trephine biopsies than in smears.