R
Rabih S. Talhouk
Researcher at American University of Beirut
Publications - 85
Citations - 3660
Rabih S. Talhouk is an academic researcher from American University of Beirut. The author has contributed to research in topics: Breast cancer & Extracellular matrix. The author has an hindex of 26, co-authored 83 publications receiving 3426 citations. Previous affiliations of Rabih S. Talhouk include Ohio State University & University of California, San Francisco.
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Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution
TL;DR: The balance of ECM- degrading proteinases and their inhibitors regulates the organization of the basement membrane and the tissue-specific function of the mammary gland by maintaining high concentrations of TIMP protein with the use of surgically implanted slow-release pellets.
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Targeted Expression of Stromelysin-1 in Mammary Gland Provides Evidence for a Role of Proteinases in Branching Morphogenesis and the Requirement for an Intact Basement Membrane for Tissue-specific Gene Expression
Carolyn J. Sympson,Rabih S. Talhouk,C M Alexander,Jennie R. Chin,S M Clift,Mina J. Bissell,Zena Werb +6 more
TL;DR: It is concluded that the balance of ECM-degrading enzymes with their inhibitors, and the associated regulation ofECM structure, is crucial for tissue- specific gene expression and morphogenesis in vivo.
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Screening of selected indigenous plants of Lebanon for antimicrobial activity.
Elie K. Barbour,Mohammed Al Sharif,Vatche K. Sagherian,A. Habre,Rabih S. Talhouk,Salma N. Talhouk +5 more
TL;DR: The chance to find antimicrobial activities was more apparent in methanol rather than water extracts of the same indigenous plants of Lebanon, with higher antimacterial activities in 20 microl methanolate extract-discs in comparison to that present in the 10 microl discs.
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Connexins: a myriad of functions extending beyond assembly of gap junction channels
TL;DR: This review provides an updated overview of current knowledge of connexins and their interacting proteins, and it describes connexin modulation in disease and tumorigenesis.
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Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture
TL;DR: The temporal pattern of expression of these proteinases and the basal secretion of gelatinases by epithelial cells suggest their involvement in the remodelling of the extracellular matrix during the different stages of mammary development and thus modulation of Mammary cell function.