Rachel F. Brem

TL;DR: Because ADH was underdiagnosed in 25% of the lesions, it is recommended that surgical excision be performed whenever ADH is found in tissue obtained from 11-gauge directional vacuum-assisted breast biopsy.

TL;DR: Breast ultrasound for the detection of breast cancer in the screening environment, as well as strategies for integrating screening breast ultrasound, including automated breast ultrasound are discussed.

TL;DR: BSIG has high sensitivity and moderate specificity helping detect breast cancers and helped detect occult cancer not visualized at mammography or ultrasonography in six patients.

TL;DR: All patients with lobular neoplasia at core or vacuum-assisted biopsy should undergo surgical excision until further differentiating criteria can be determined, and significant sampling error occurs regardless of the type of core biopsy device, number of specimens obtained, histologic-radiographic concordance, mammographic appearance, and complete excision of the lesion as determined by imaging.

TL;DR: The findings suggest that miR-638 plays an important role in TNBC progression via BRCA1 deregulation, and might serve as a potential prognostic biomarker and therapeutic target for breast cancer.