R
Raghuveer Ramachandra
Researcher at West Virginia University
Publications - 32
Citations - 428
Raghuveer Ramachandra is an academic researcher from West Virginia University. The author has contributed to research in topics: Immune checkpoint & Immune system. The author has an hindex of 9, co-authored 32 publications receiving 326 citations.
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Journal ArticleDOI
Cloning and characterization of microRNAs from rainbow trout (Oncorhynchus mykiss): Their expression during early embryonic development
TL;DR: The data support the notion that Dicer processes miRNAs and Stat3 induces expression of miR-21 and possibly other mi RNAs during EGA, which in turn guide maternal mRNAs for degradation, which is required for normal embryonic development.
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PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.
Pottayil G. Sasikumar,Naremaddepalli S. Sudarshan,Sreenivas Adurthi,Raghuveer Ramachandra,Dodderi S. Samiulla,Anirudha Lakshminarasimhan,Anuradha Ramanathan,Talapaneni Chandrasekhar,Amit A. Dhudashiya,Sumalatha Rani Talapati,Nagesh Gowda,Sreenivasulareddy Palakolanu,Jiju Mani,Bandi Srinivasrao,David Joseph,Nigam Kumar,Rashmi Nair,Hanudatta S. Atreya,Nagaraj Gowda,Murali Ramachandra +19 more
TL;DR: CA-170 as mentioned in this paper is an amino acid inspired small molecule inhibitor of PD-L1 and VISTA derived from the interface of the PD-1 and PD-l1.
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Molecular characterization and expression profiles of cyclin B1, B2 and Cdc2 kinase during oogenesis and spermatogenesis in rainbow trout (Oncorhynchus mykiss)
TL;DR: Data suggest that CB1 may have a leading role in the regulation of meiotic maturation of oocytes and spermotocytes, but CB1 protein varies in amount during these processes.
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A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy.
Pottayil G. Sasikumar,Raghuveer Ramachandra,Sreenivas Adurthi,Amit A. Dhudashiya,Sureshkumar Vadlamani,Koteswararao Vemula,Sriharibabu Vunnum,Leena Khare Satyam,Dodderi S. Samiulla,Krishnaprasad Subbarao,Rashmi Nair,Rajeev K. Shrimali,Nagaraj Gowda,Murali Ramachandra +13 more
TL;DR: NP-12 is the first rationally designed peptide therapeutic targeting PD-1 signaling pathways exhibiting immune activation, excellent antitumor activity, and potential for better management of irAEs.
Journal Article
Identification of AFLP markers linked to sterility mosaic disease in pigeonpea Cajanus cajan (L.) Millsp.
TL;DR: BSA was employed to identify simple sequence repeats (SSR) and amplified fragment length polymorphism (AFLP) markers associated with sterility mosaic disease (SMD) resistance in the F2 population of the cross involving TTB 7 (susceptible) and BRG 3 (resistant) parents.