R
Raheleh Halabian
Researcher at Baqiyatallah University of Medical Sciences
Publications - 110
Citations - 1741
Raheleh Halabian is an academic researcher from Baqiyatallah University of Medical Sciences. The author has contributed to research in topics: Mesenchymal stem cell & Chemistry. The author has an hindex of 17, co-authored 93 publications receiving 1200 citations. Previous affiliations of Raheleh Halabian include Tehran University of Medical Sciences & Tarbiat Modares University.
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A revealing review of mesenchymal stem cells therapy, clinical perspectives and Modification strategies
TL;DR: Recent research findings of the clinical applications and therapeutic potential of this cell type, MSCs' mechanisms of therapy, strategies to improve their therapeutic potentials such as manipulations and preconditioning, and potential/unexpected risks which should be considered as a prerequisite step before clinical use are focused on.
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Nrf-2 overexpression in mesenchymal stem cells reduces oxidative stress-induced apoptosis and cytotoxicity.
Mohammad Mohammadzadeh,Raheleh Halabian,Ahmad Gharehbaghian,Naser Amirizadeh,Ali Jahanian-Najafabadi,Amaneh Mohammadi Roushandeh,Mehryar Habibi Roudkenar +6 more
TL;DR: Transient expression of Nrf2 by MSCs protected them against cell death and the apoptosis triggered by hypoxic and oxidative stress conditions, and indicates that management of cellular stress responses can be used for practical applications.
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Neutrophil Gelatinase-associated Lipocalin Acts as a Protective Factor against H2O2 Toxicity
Mehryar Habibi Roudkenar,Raheleh Halabian,Zahra Ghasemipour,Amaneh Mohammadi Roushandeh,Mahdi Rouhbakhsh,Mahin Nekogoftar,Yoshikazu Kuwahara,Manabu Fukumoto,Mohammad Ali Shokrgozar +8 more
TL;DR: The results revealed for the first time a new function for NGAL/Lcn2: acting as a protective factor against H( 2)O(2) toxicity and may have the potential application to ameliorate the toxicity induced by oxidative stress conditions.
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Lipocalin 2 regulation by thermal stresses: protective role of Lcn2/NGAL against cold and heat stresses.
Mehryar Habibi Roudkenar,Raheleh Halabian,Amaneh Mohammadi Roushandeh,Mohammad Reza Nourani,Nasser Masroori,Majid Ebrahimi,Mahin Nikogoftar,Mehdi Rouhbakhsh,Parisa Bahmani,Ali Jahanian Najafabadi,Mohammad Ali Shokrgozar +10 more
TL;DR: The induction of Lcn2 by thermal stresses in vivo and its role following exposure to cold and heat stresses in vitro may have the potential to improve cell proliferation and preservation particularly to prevent cold ischemia injury of transplanted organs or for treatment of some cancers by hyperthermia.
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Nisin, a potent bacteriocin and anti-bacterial peptide, attenuates expression of metastatic genes in colorectal cancer cell lines.
TL;DR: Nisin could suppressed metastatic process via down-regulation of CEA, CEAM6, MMP2F, M MP9F genes, which play a role in the prevention local tumor invasion, metastasis and recurrence.