Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

Bromination is one of the most important transformations in organic synthesis and can be carried out using bromine and many other bromo compounds. Use of molecular bromine in organic synthesis is well-known. However, due to the hazardous nature of bromine, enormous growth has been witnessed in the past several decades for the development of solid bromine carriers. This review outlines the use of bromine and different bromo-organic compounds in organic synthesis. The applications of bromine, a total of 107 bromo-organic compounds, 11 other brominating agents, and a few natural bromine sources were incorporated. The scope of these reagents for various organic transformations such as bromination, cohalogenation, oxidation, cyclization, ring-opening reactions, substitution, rearrangement, hydrolysis, catalysis, etc. has been described briefly to highlight important aspects of the bromo-organic compounds in organic synthesis.

Use of Bromine and Bromo-Organic Compounds in Organic Synthesis

Centro de Quı́mica-Fı́sica Molecular (CQFM) and Institute of Nanosciences and Nanotechnology (IN), Departamento de Engenharia Quı́mica e Biológica, Instituto Superior Técnico, 1049-001 Lisboa, Portugal, REQUIMTE, Departamento de Quı́mica, Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Quinta da Torre, 2829-516 Caparica, Portugal, and iMed.UL, Faculdade de Farmácia da Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

More sustainable approaches for the synthesis of N-based heterocycles.

Deep eutectic solvents (DESs) as eco-friendly and sustainable solvent/catalyst systems in organic transformations

Dry reaction of indoles with carbonyl compounds on montmorillonite K10 clay: a mild, expedient synthesis of diindolylalkanes and vibrindole A

Microwave-assisted Michael reactions of 3-(2′-nitrovinyl)indole with indoles on TLC-grade silica gel. A new, facile synthesis of 2,2-bis(3′-indolyl)nitroethanes

The different synthetic routes to diindolylalkanes (DIAs), an important class of synthetic and natural products, their merits and demerits and the properties of the bioactive DIAs have been presented in this review which is the first of its kind in this field. The synthesis of the bioactive DIAs (3), streptindole (4), vibrindole A (6), 10 and 11 has also been included in this review.

A Sojourn in the Synthesis and Bioactivity of Diindolylalkanes

Michael reaction of indoles with 3-(2′-nitrovinyl)indole under solvent-free conditions and in solution. An efficient synthesis of 2,2-bis(indolyl)nitroethanes and studies on their reduction

Ramkrishna Basak

Papers

Dry reaction of indoles with carbonyl compounds on montmorillonite K10 clay: a mild, expedient synthesis of diindolylalkanes and vibrindole A

Microwave-assisted Michael reactions of 3-(2′-nitrovinyl)indole with indoles on TLC-grade silica gel. A new, facile synthesis of 2,2-bis(3′-indolyl)nitroethanes

A Sojourn in the Synthesis and Bioactivity of Diindolylalkanes

Michael reaction of indoles with 3-(2′-nitrovinyl)indole under solvent-free conditions and in solution. An efficient synthesis of 2,2-bis(indolyl)nitroethanes and studies on their reduction

A facile and efficient synthesis of 2,2-bis(3'/2'-indolyl)ethylamines and three bisindolic natural products