R
Ran Xu
Publications - 14
Citations - 5003
Ran Xu is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications receiving 3910 citations.
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Identification of lactate metabolism-related subtypes and development of a lactate-related prognostic indicator of lung adenocarcinoma
TL;DR: The effect of lactate metabolism on the prognosis of LUAD patients is validated, and a lactate-related prognostic indicator (LRPI) is established that can predict LUAD patient survival, molecular characteristics and response to therapy, which can aid the individualized treatment ofLUAD patients.
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Identification of tumor antigens and immune subtypes in lung squamous cell carcinoma for mRNA vaccine development
TL;DR: Among the highly mutated genes in LUSC, bone morphogenetic protein 5 (BMP5) and claudin 5 (CLDN5) expression were positively correlated with antigen-presenting cell infiltration, which indicates that these 2 genes have potential for development as mRNA cancer vaccines.
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Multi-omics analysis to identify lung squamous carcinoma lactate metabolism-related subtypes and establish related index to predict prognosis and guide immunotherapy
TL;DR: In this paper , the authors identified two subtypes with different lactate metabolism patterns in lung squamous carcinoma (LUSC) by non-negative matrix factorization and explored their multi-omics features.
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Mitochondrial Homeostasis–Related lncRNAs are Potential Biomarkers for Predicting Prognosis and Immune Response in Lung Adenocarcinoma
Bo Peng,Han Lou,Chen Chen,Lei Wang,Huawei Li,Tong Lu,Ruisi Na,Ran Xu,Tong Xin,Lingqi Yao,Henghui Xu,Kaiyu Wang,Xin Liu,Linyou Zhang +13 more
TL;DR: The established MHLncSig may be a promising tool for predicting the prognosis and guiding individualized treatment in LUAD and validated the expression trends of lncRNAs included in the risk model using quantitative real-time polymerase chain reaction (qRT-PCR) assays.
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Tumor Characteristics Associated with Lymph Node Metastasis and Prognosis in Patients with ERBB2-Positive Gastric Cancer
TL;DR: It is found that risk factors for lymph node metastasis included tumor size, neural invasion, and vascular invasion were significant prognostic variables, and shed new light on the pathology and prognosis of patients with ERBB2-positive GC.