Ran Zhao

TL;DR: The TMAO-involved mechanisms of atherosclerotic CVD from the perspective of inflammation, inflammation-related immunity, cholesterol metabolism, and atherothrombosis are discussed.

TL;DR: It is demonstrated that both high and low-dose BBR can improve serum lipid and systemic inflammation levels, and alleviate atherosclerosis induced by high-fat diet in ApoE–/– mice.

TL;DR: The role of ER stress in different types of cells in atherosclerotic lesions includes the activation of apoptotic and inflammatory pathways induced by prolonged ER stress, especially in advanced lesional macrophages and endothelial cells (ECs), as well as common atherosclerosis-related ER stressors in different lesional cells.

TL;DR: In this paper, the authors proposed a new target in the treatment of atherosclerosis, which is closely related to mitochondrial dynamics, such as steroid biosynthesis, calcium homeostasis, immune cell activation, redox signaling, apoptosis, and inflammation.

TL;DR: Wang et al. as discussed by the authors used a network pharmacology analysis approach to elucidate the molecular mechanism of HSHP in the treatment of Coronary heart disease (CHD), which may be closely related to the fluid shear force, lipid metabolism, and inflammatory response.