R
Raymond Wai-Yin Sun
Researcher at Shantou University
Publications - 72
Citations - 4744
Raymond Wai-Yin Sun is an academic researcher from Shantou University. The author has contributed to research in topics: Cisplatin & Porphyrin. The author has an hindex of 36, co-authored 71 publications receiving 4192 citations. Previous affiliations of Raymond Wai-Yin Sun include University of Hong Kong.
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Journal Article
Silver nanoparticles inhibit hepatitis B virus replication.
Lei Lu,Raymond Wai-Yin Sun,Rong Chen,Chee-Kin Hui,Chi-Ming Ho,John M. Luk,George K. K. Lau,Chi-Ming Che +7 more
TL;DR: Silver nanoparticles could inhibit the in vitro production of HBV RNA and extracellular virions and hypothesize that the direct interaction between these nanoparticles and HBV double-stranded DNA or viral particles is responsible for their antiviral mechanism.
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Silver nanoparticles fabricated in Hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells.
Raymond Wai-Yin Sun,Rong Chen,Nancy P. Y. Chung,Chi-Ming Ho,Chen-Lung Steve Lin,Chi-Ming Che +5 more
TL;DR: Silver nanoparticles fabricated in Hepes buffer exhibit potent cytoprotective and post-infected anti-HIV-1 activities toward Hut/CCR5 cells.
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Gold(III) porphyrins as a new class of anticancer drugs: cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells.
TL;DR: A series of gold tetraarylporphyrins are stable in the presence of glutathione and exert much higher potency than cisplatin in killing human cancer cells, including the drug-resistant variants.
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The anti-cancer properties of gold(III) compounds with dianionic porphyrin and tetradentate ligands
Raymond Wai-Yin Sun,Chi-Ming Che +1 more
TL;DR: The in vitro and in vivo anti- cancer efficacy, as well as the anti-cancer mechanisms of the most potent gold(III) porphyrin compound [Au III (TPP)]Cl ( 1a) are detailed.
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Gold(III) Porphyrin 1a Induced Apoptosis by Mitochondrial Death Pathways Related to Reactive Oxygen Species
TL;DR: Results support a role for gold(III) porphyrin 1a as a promising anticancer drug lead and as a possible novel therapeutic agent directed toward the mitochondria.