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Regina Menezes
Researcher at Universidade Nova de Lisboa
Publications - 54
Citations - 6817
Regina Menezes is an academic researcher from Universidade Nova de Lisboa. The author has contributed to research in topics: Saccharomyces cerevisiae & Transcription factor. The author has an hindex of 21, co-authored 52 publications receiving 6071 citations. Previous affiliations of Regina Menezes include Academy of Sciences of the Czech Republic & University of Düsseldorf.
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Journal ArticleDOI
Overview of Beneficial Effects of (Poly)phenol Metabolites in the Context of Neurodegenerative Diseases on Model Organisms.
Diogo Carregosa,Sara Mota,Sofia Ferreira,Beatriz Alves-Dias,Natasa Loncarevic-Vasiljkovic,Natasa Loncarevic-Vasiljkovic,Carolina Lage Crespo,Regina Menezes,Rita O. Teodoro,Cláudia N. Santos +9 more
TL;DR: In this paper, a review of different model organisms that have been used to study how low molecular weight (poly)phenol metabolites affect neuronal related mechanisms gathering critical insight on their potential to tackle the major hallmarks of neurodegeneration.
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Polyphenols and Their Metabolites in Renal Diseases: An Overview
Íris Cláudia Felisberto Guerreiro,Cíntia Ferreira-Pêgo,Diogo Carregosa,Cláudia N. Santos,Regina Menezes,Ana Serra Fernandes,João G. Costa +6 more
TL;DR: An overview of the published data regarding the potential beneficial effects of polyphenols on major kidney diseases, namely acute kidney injury, chronic kidney disease, diabetic nephropathy, renal cancer, and drug-induced nephrotoxicity is provided.
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Assessing the Intestinal Permeability and Anti-Inflammatory Potential of Sesquiterpene Lactones from Chicory.
Melanie S. Matos,José D Anastácio,J. William Allwood,Diogo Carregosa,Daniela Marques,Julie Sungurtas,Gordon J. McDougall,Regina Menezes,Ana A. Matias,Derek Stewart,Cláudia N. Santos +10 more
TL;DR: The SL with the highest anti-inflammatory potential was 11β,13-dihydrolactucin, which inhibited up to 54% of Calcineurin-responsive zinc finger activation, concomitantly with the impairment of the nuclear accumulation of Crz1, the yeast orthologue of human NFAT.
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Inhibition of Yap2 activity by MAPKAP kinase Rck1 affects yeast tolerance to cadmium.
Daiane Mazzola,Daiane Mazzola,Catarina Pimentel,Soraia M. Caetano,Catarina Amaral,Regina Menezes,Cláudia N. Santos,Elis C. A. Eleutherio,Claudina Rodrigues-Pousada +8 more
TL;DR: It is suggested that in response to cadmium stress Yap2 may serve a dual purpose: oxidative stress attenuation and cell wall maintenance.
Journal ArticleDOI
Mediator, SWI/SNF and SAGA complexes regulate Yap8-dependent transcriptional activation of ACR2 in response to arsenate.
Regina Menezes,Catarina Pimentel,Ana Rita Silva,Catarina Amaral,Jawad Merhej,Frédéric Devaux,Claudina Rodrigues-Pousada +6 more
TL;DR: It is here reported for the first time the essential role of the Mediator complex in the transcriptional activation of ACR2 by Yap8, and an order-of-function map is proposed to recapitulate the sequence of events taking place in cells injured with arsenate.