Reinhard Putz

TL;DR: It is suggested that human cartilage deforms very little in vivo during physiological activities and recovers from deformation within 90 min after loading, and potential reasons for the inability of cartilage to adapt to mechanical stimuli include a lack of evolutionary pressure and a decoupling of mechanical competence and tissue mass.

TL;DR: The hypothesis that knee cartilage becomes thinner during aging, in the absence of cartilage disease, is confirmed, but that the amount of reduction differs between sexes and between compartments of the knee joint.

TL;DR: Data from a systematic study into cartilage compression of intact human femoro-patellar joints under short- and long-term static loading with MR imaging may be used to compute the load partitioning between the solid matrix and fluid phase, and to elucidate the etiologic factors relevant in mechanically induced osteoarthritis.

TL;DR: It is shown that fat-suppressed gradient echo sequences permit valid analysis of cartilage morphology, both in healthy and severely osteoarthritic joints, as well as highly reproducible measurements, and Quantitative analyses of magnetization transfer and proton density hold promise for biochemical evaluation of articular cartilage, and are shown to be related to the deformational behavior of the cartilage.

TL;DR: In the knee joint, 3D reconstructions of the cartilages, and measurements that take into account the out‐of‐plane deviation of the interface normals (3D MR‐CCM), are required.