R
Réjean Langlois
Researcher at Université de Sherbrooke
Publications - 44
Citations - 2068
Réjean Langlois is an academic researcher from Université de Sherbrooke. The author has contributed to research in topics: Phthalocyanine & Singlet oxygen. The author has an hindex of 25, co-authored 44 publications receiving 2026 citations.
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Biological activities of phthalocyanines‐x. syntheses and analyses of sulfonated phthalocyanines
TL;DR: Synthetic methods to obtain selectively sulfonated metallo phthalocyanines are compared, finding that both condensation and direct sulfonation procedures lead to mixtures of mono‐ to tetrasulfonated products which are resolved by reverse phase liquid chromatography in buffered aqueous‐methanol.
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Biological activities of phthalocyanines—iv. type ii sensitized photooxidation of l-tryptophan and cholesterol by sulfonated metallo phthalocyanines
TL;DR: Support for the involvement of singlet excited oxygen is obtained from azide inhibition and the formation of the specific singlet oxygen product with cholesterol in the case of the manganese complex.
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Biological activities of phthalocyanines--VIII. Cellular distribution in V-79 Chinese hamster cells and phototoxicity of selectively sulfonated aluminum phthalocyanines.
TL;DR: Water soluble chloro aluminum phthalocyanines sulfonated to different degrees are studied for phototoxicity and cellular distribution in V–79 Chinese hamster cells and it was revealed that the dye was uniformly distributed in the cytoplasm but absent in the nucleus.
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Biological activities of phthalocyanines. IX: Photosensitization of V-79 Chinese hamster cells and EMT-6 mouse mammary tumor by selectively sulfonated zinc phthalocyanines
TL;DR: The disulfonated zinc phthalocyanine showed the best tumoricidal activity in the series and appeared to be a more efficient photosensitizer of cell inactivation and tumor cure than the aluminum or gallium complexes as well as hematoporphyrin derivative preparations.
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Biological activities of phthalocyanines--VI. Photooxidation of L-tryptophan by selectively sulfonated gallium phthalocyanines: singlet oxygen yields and effect of aggregation.
TL;DR: The photosensitized oxidation of L‐tryptophan by gallium phthalocyanines sulfonated to different degrees is studied as a function of both substrate and sensitizer concentrations in water and 50% MeOH‐H2O solutions.