R
Renate Urbaschek
Researcher at Heidelberg University
Publications - 30
Citations - 963
Renate Urbaschek is an academic researcher from Heidelberg University. The author has contributed to research in topics: Kupffer cell & Alcoholic liver disease. The author has an hindex of 19, co-authored 30 publications receiving 952 citations.
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Journal ArticleDOI
The microcirculation during endotoxemia
TL;DR: The microvascular responses to endotoxemia are reviewed and some of the mechanisms involved are discussed, including eicosanoids, cytokines, chemokines, adhesion molecules, reactive free radicals, platelet-activating factor, and nitric oxide.
Journal ArticleDOI
Endotoxin, endotoxin-neutralizing-capacity, sCD14, sICAM-1, and cytokines in patients with various degrees of alcoholic liver disease.
Renate Urbaschek,Robert S. McCuskey,Volker Rudi,K.-P. Becker,Felix Stickel,Bernhard Urbaschek,Helmut K. Seitz +6 more
TL;DR: The limited capacity of plasma to neutralize endotoxin in liver injury seems to be an important factor in ALD which may be responsible for the release of endotoxin-induced mediators, such as cytokines, as well as s-ICAM-1, that are relevant in the pathogenesis of ALD.
Journal ArticleDOI
Kupffer cell function in host defense.
TL;DR: The intrahepatic density and level of activation of Kupffer cells were found to play a role in determining endotoxin sensitivity and to be involved, in conjunction with endotoxin, in the development of tolerance.
Journal ArticleDOI
Species differences in Kupffer cells and endotoxin sensitivity.
TL;DR: The results suggests that the intrahepatic density and the level of activation of Kupffer cells participate in determining endotoxin sensitivity.
Journal ArticleDOI
Serum collagen type VI and XIV and hyaluronic acid as early indicators for altered connective tissue turnover in alcoholic liver disease.
Felix Stickel,Renate Urbaschek,Detlef Schuppan,Gudrun Poeschl,Christine Oesterling,Christian Conradt,Robert S. McCuskey,Ulrich A. Simanowski,Helmut K. Seitz +8 more
TL;DR: Collagens VI, and XIV, procollagen-III-N-propeptide, and hyaluronic acid appear to be sensitive markers indicating fibrotic transformation in alcoholics.