R
Reza Rahimian
Researcher at Douglas Mental Health University Institute
Publications - 89
Citations - 2484
Reza Rahimian is an academic researcher from Douglas Mental Health University Institute. The author has contributed to research in topics: Tropisetron & Seizure threshold. The author has an hindex of 29, co-authored 82 publications receiving 1991 citations. Previous affiliations of Reza Rahimian include McGill University & Mashhad University of Medical Sciences.
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Journal ArticleDOI
Medicinal Chemistry of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors
Ubaldina Galli,Cristina Travelli,Alberto Massarotti,Gohar Fakhfouri,Reza Rahimian,Gian Cesare Tron,Armando A. Genazzani +6 more
TL;DR: There is now ample evidence that NAMPT is secreted and has a role as a cytokine, and a surge in interest in the synthesis of novel molecules has occurred in this field.
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WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.
TL;DR: Findings indicate that WIN exerts neuroprotective and anti-inflammatory actions against Aβ damage through both CB⁁ and CB₁ receptor subtype partially attenuated the protective effects.
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The role of serotonin in memory: interactions with neurotransmitters and downstream signaling.
TL;DR: The serotonin-induced modulation of various systems involved in mnesic function including cholinergic, dopaminergic, GABAergic, glutamatergic transmissions as well as amyloidogenesis and intracellular pathways are discussed.
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Anti-inflammatory effects of 5-HT receptor antagonist, tropisetron on experimental colitis in rats.
TL;DR: The aim of this study was to investigate the effects of tropisetron, a 5‐Hydroxytryptamine (5‐HT)‐3 receptor antagonist with anti‐inflammatory properties in a model of experimental colitis in rat.
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Morphine is protective against doxorubicin-induced cardiotoxicity in rat
Roohollah Babaei Kelishomi,Shahram Ejtemaee-Mehr,Seyed Mohammad Tavangar,Reza Rahimian,Jalal Izadi Mobarakeh,Jalal Izadi Mobarakeh,Ahmad Reza Dehpour +6 more
TL;DR: Since morphine had very good protective effects against a high dose of DOX given as a multiple, low, unitary dose regimen, not only on the heart but on the whole rat as well, it could be recommended for further investigation in this potentially new indication for clinical application.