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Showing papers by "Richard T. Ramsden published in 1977"


Journal ArticleDOI
TL;DR: Patients with a fluctuating hearing loss, episodic vertigo and tinnitus with no known aetiological cause were investigated as cases of Menière's disorder and transtympanic electrocochleography was found to be helpful in reaching the diagnosis of an inner ear disorder.
Abstract: Patients with a fluctuating hearing loss, episodic vertigo and tinnitus with no known aetiological cause were investigated as cases of Meniere's disorder. Transtympanic electrocochleography was found to be helpful in reaching the diagnosis of an inner ear disorder. In 65% of the patients, a large DC potential was recorded which caused an apparent widening of the summating potential/action potential (SP/AP) waveform. This potential was thought to be an SP which enhanced relative to the AP component, and believed to be related directly to the presence of endolymphatic hydrops. A method is described which 'scores' the clinical history with respect to certainty of the diagnosis of Meieere's disorder. It was found that the more certain cases, with high scores, were statistically more likely to show an abnormal SP/AP waveform. The results of endolymphatic sac surgery were also assessed over 1 year in 28 cases, and it was found that those patients whose ECochG had revealed an abnormal SP/AP waveform prior to surgery benefitted in a statistically significant manner more from the operation.

185 citations


Journal ArticleDOI
TL;DR: Experience is described of the use of iontophoresis of 2% lignocaine to achieve effective tympanic membrane anaesthesia for outpatient myringotomy and transtympanic electrocochleography.
Abstract: Experience is described of the use of iontophoresis of 2% lignocaine to achieve effective tympanic membrane anaesthesia. The main uses are for outpatient myringotomy and transtympanic electrocochleography. Complete anaesthesia of the drum has been obtained in all cases, and those patients who had previously had these procedures carried out without anaesthetic, or with surface 'anaesthesia' only, all stated a marked preference for iontophoresis. No complications have occurred.

52 citations


Journal ArticleDOI
TL;DR: Analysis of middle ear function by acoustic impedance measurements suggests a decrease in the stiffness of the transducer mechanism in rheumatoid arthritis.
Abstract: Analysis of middle ear function has for many years been accomplished by acoustic impedance measurements and this has proved of great clinical value. The vectors which contribute to impedance are functions of mass, stiffness and resistance of the system and information about these components may be obtained by use of the otoadmittance meter. The shape of the tympanogram may be altered both by pathologies which change the relative magnitude of the vectors and by variation in the probe tone frequency. Patients with rheumatoid arthritis (55 ears) were compared with a series of controls (50 ears); 38% of 'rheumatoid ears' demonstrated a marked notch on the 660 Hz susceptance curve whilst only 8% of the control group showed this abnormality. The pattern suggests a decrease in the stiffness of the transducer mechanism in rheumatoid arthritis.

34 citations


Journal ArticleDOI
TL;DR: It is a common misconception that damage to the marginal mandibular branch of the facial nerve causes drooping of the corner of the mouth, but this is not true, as a consideration of the anatomy confirms.
Abstract: It is a common misconception that damage to the marginal mandibular branch of the facial nerve causes drooping of the corner of the mouth. In fact the opposite is true, as a consideration of the anatomy confirms.

31 citations


Journal ArticleDOI
29 Jan 1977-BMJ
TL;DR: Electrocochleography was performed on three patients to monitor the intravenous administration of tobramycin and an immediate dramatic reduction in cochlear output was observed, which recovered fully as serum levels fell.
Abstract: Electrocochleography was performed on three patients to monitor the intravenous administration of tobramycin. When peak serum tobramycin levels exceeded 8-10 mug/ml an immediate dramatic reduction in cochlear output was observed, which recovered fully as serum levels fell. The patients had no auditory or vestibular symptoms either during or after treatment.

26 citations


Journal ArticleDOI
TL;DR: A double blind trial was carried out comparing S-CMC with inert placebo in the treatment of glue ear in fifty-two children who had not previously undergone surgery for the condition.
Abstract: A double blind trial was carried out comparing S-carboxymethylcysteine (S-CMC; Mucodyne, Berk Pharmaceuticals) with inert placebo in the treatment of glue ear in fifty-two children who had not previously undergone surgery for the condition. The results, analysed after three months of treatment failed to demonstrate a significant reduction in the number of children receiving S-CMC who eventually required surgery for the condition.

15 citations