scispace - formally typeset
Search or ask a question
Author

Richard White

Bio: Richard White is an academic researcher from Stanford University. The author has contributed to research in topics: Gonadotropin-releasing hormone & Environmental history. The author has an hindex of 40, co-authored 105 publications receiving 6723 citations. Previous affiliations of Richard White include University of Geneva & Michigan State University.


Papers
More filters
Book
01 Jan 1991
TL;DR: In this article, the authors describe a world made of fragments, and the middle ground as a "fragmentation" of the world made up of fragments: refugees, the fur trade, the clash of empires, the contest of villagers, the British alliance, the Confederacies, etc.
Abstract: List of abbreviations Introduction 1. Refugees: a world made of fragments 2. The middle ground 3. The fur trade 4. The alliance 5. Republicans and rebels 6. The clash of empires 7. Pontiac and the restoration of the middle ground 8. The British alliance 9. The contest of villagers 10. Confederacies 11. The politics of benevolence Epilogue Index.

713 citations

Journal ArticleDOI
TL;DR: The middle ground: Indians, empires, and republics in the Great Lakes region, 1650-1815 / Richard White as mentioned in this paper, 20th anniversary edition, Cambridge : Cambridge University Press, 2011.
Abstract: E99 .A35 W48 2011 Title: The middle ground : Indians, empires, and republics in the Great Lakes region, 1650-1815 / Richard White. Edition: 20th anniversary edition. Publication info: Cambridge : Cambridge University Press, 2011. Subject: Algonquins--Great Lakes Region (North America)--History. Subject: Algonquins--First contact with Europeans--Great Lakes Region (North America). Subject: Algonquian Indians--Great Lakes Region (North America)--History. Series: Cambridge studies in North American Indian history. Location: Reserves

447 citations

Journal ArticleDOI
TL;DR: Molecular phylogenetic analysis shows that this second GnRH-II gene is likely the result of a duplication before the appearance of vertebrates, and predicts the existence of a third GnRH form in humans and other vertebrates.
Abstract: Gonadotropin-releasing hormone (GnRH) is a decapeptide widely known for its role in regulating reproduction by serving as a signal from the hypothalamus to pituitary gonadotropes. In addition to hypothalamic GnRH (GnRH-I), a second GnRH form (pGln-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly; GnRH-II) with unknown function has been localized to the midbrain of many vertebrates. We show here that a gene encoding GnRH-II is expressed in humans and is located on chromosome 20p13, distinct from the GnRH-I gene that is on 8p21-p11.2. The GnRH-II genomic and mRNA structures parallel those of GnRH-I. However, in contrast to GnRH-I, GnRH-II is expressed at significantly higher levels outside the brain (up to 30×), particularly in the kidney, bone marrow, and prostate. The widespread expression of GnRH-II suggests it may have multiple functions. Molecular phylogenetic analysis shows that this second gene is likely the result of a duplication before the appearance of vertebrates, and predicts the existence of a third GnRH form in humans and other vertebrates.

418 citations

Book
01 Jan 1981
TL;DR: The authors argued that these images, rather than describing an especially Australian reality, grow out of assumptions about nature, race, class, democracy, sex and empire, and are 'invented' to serve the interests of particular groups.
Abstract: 'White sets himself a most ambitious task, and he goes remarkably far to achieving his goals. Very few books tell so much about Australia, with elegance and concision, as does his' - Professor Michael Roe'Stimulating and informative. an antidote to the cultural cringe' - Canberra Times'To be Australian': what can that mean? Inventing Australia sets out to find the answers by tracing the images we have used to describe our land and our people - the convict hell, the workingman's paradise, the Bush legend, the 'typical' Australian from the shearer to the Bondi lifesaver, the land of opportunity, the small rich industrial country, the multicultural society.The book argues that these images, rather than describing an especially Australian reality, grow out of assumptions about nature, race, class, democracy, sex and empire, and are 'invented' to serve the interests of particular groups.There have been many books about Australia's national identity; this is the first to place the discussion within an historical context to explain how Australians' views of themselves change and why these views change in the way they do.

300 citations


Cited by
More filters
Journal ArticleDOI
01 Oct 1987-Genomics
TL;DR: A computer package, called MAPMAKER, designed specifically for the construction of linkage maps in a number of organisms, including the human and several plants, and it is outlined the mapping strategies that have been used.

6,745 citations

Journal ArticleDOI
TL;DR: A primer pair is presented that eliminates the problem of presumed impossible to measure telomeres in vertebrate DNA by PCR amplification with oligonucleotide primers designed to hybridize to the TTAGGG and CCCTAA repeats, allowing simple and rapid measurement of telomere length in a closed tube, fluorescence-based assay.
Abstract: It has long been presumed impossible to measure telomeres in vertebrate DNA by PCR amplification with oligonucleotide primers designed to hybridize to the TTAGGG and CCCTAA repeats, because only primer dimer-derived products are expected. Here we present a primer pair that eliminates this problem, allowing simple and rapid measurement of telomeres in a closed tube, fluorescence-based assay. This assay will facilitate investigations of the biology of telomeres and the roles they play in the molecular pathophysiology of diseases and aging.

3,014 citations

Journal ArticleDOI
24 May 1996-Science
TL;DR: Plasma viral load was a better predictor of progression to AIDS and death than was the number of CD4+ T cells, and the risk of acquired immunodeficiency syndrome (AIDS) and death in study subjects was directly related to plasma viral load at study entry.
Abstract: The relation between viremia and clinical outcome in individuals infected with human immunodeficiency virus-type 1 (HIV-1) has important implications for therapeutic research and clinical care. HIV-1 RNA in plasma was quantified with a branched-DNA signal amplification assay as a measure of viral load in a cohort of 180 seropositive men studied for more than 10 years. The risk of acquired immunodeficiency syndrome (AIDS) and death in study subjects, including those with normal numbers of CD4+ T cells, was directly related to plasma viral load at study entry. Plasma viral load was a better predictor of progression to AIDS and death than was the number of CD4+ T cells.

2,772 citations

Journal ArticleDOI
TL;DR: The fish gill is a multipurpose organ that, in addition to providing for aquatic gas exchange, plays dominant roles in osmotic and ionic regulation, acid-base regulation, and excretion of nitrogenous wastes.
Abstract: The fish gill is a multipurpose organ that, in addition to providing for aquatic gas exchange, plays dominant roles in osmotic and ionic regulation, acid-base regulation, and excretion of nitrogenous wastes Thus, despite the fact that all fish groups have functional kidneys, the gill epithelium is the site of many processes that are mediated by renal epithelia in terrestrial vertebrates Indeed, many of the pathways that mediate these processes in mammalian renal epithelial are expressed in the gill, and many of the extrinsic and intrinsic modulators of these processes are also found in fish endocrine tissues and the gill itself The basic patterns of gill physiology were outlined over a half century ago, but modern immunological and molecular techniques are bringing new insights into this complicated system Nevertheless, substantial questions about the evolution of these mechanisms and control remain

2,371 citations

Journal ArticleDOI
TL;DR: This study compared the prognostic value of plasma viral load with that of clinical, serologic, and cellular markers in a large cohort of HIV-infected men and incorporated the two most predictive markers-plasma viral load and CD4+ lymphocyte count-into a regression tree that is useful for assessing the prognosis of individual patients.
Abstract: Background: The rate of disease progression among persons infected with human immunodeficiency virus type 1 (HIV-1) varies widely, and the relative prognostic value of markers of disease activity h...

2,137 citations