R
Robert W. Holley
Researcher at Salk Institute for Biological Studies
Publications - 16
Citations - 1624
Robert W. Holley is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Epidermal growth factor & Cell division. The author has an hindex of 10, co-authored 16 publications receiving 1614 citations.
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Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor
TL;DR: It is suggested that the growth inhibitor and the type beta transforming growth factor are similar molecules that can either stimulate or inhibit cell proliferation depending on the experimental conditions.
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Control of growth of mammalian cells in cell culture
TL;DR: It is concluded that the factors that control growth are probably polypeptide hormones, or hormone-like materials, as well as a variety of low molecular weight nutrients.
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Binding, internalization, and degradation of epidermal growth factor by balb 3T3 and BP3T3 cells: relationship to cell density and the stimulation of cell proliferation.
TL;DR: The hypothesis that one cause of the diminished serum requrement of BP3T3 cells is a reduced rate of utilization of serum growth factors is supported.
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Activity of a kidney epithelial cell growth inhibitor on lung and mammary cells.
TL;DR: Preliminary studies indicate that injection of the kidney epithelial cell growth inhibitor in vivo into human mammary carcinomas growing in nude mice inhibits [3H]thymidine incorporation in the tumors.
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Serum requirements for survival of 3T3 and SV3T3 fibroblasts
TL;DR: A serum factor that is labile to the action of pepsin is required for survival of 3T3 and SV3T3 cells and this ‘survival’ factor is distinct from growth-promoting factors in serum.