R
Roslyn M. Young
Researcher at DuPont
Publications - 5
Citations - 1007
Roslyn M. Young is an academic researcher from DuPont. The author has contributed to research in topics: Analyte & Mutant. The author has an hindex of 4, co-authored 5 publications receiving 978 citations.
Papers
More filters
Journal ArticleDOI
Molecular Analysis of Dehalococcoides 16S Ribosomal DNA from Chloroethene-Contaminated Sites throughout North America and Europe
Edwin R. Hendrickson,Jo Ann Payne,Roslyn M. Young,Mark G. Starr,Michael P. Perry,Stephen R. Fahnestock,David E. Ellis,Richard C. Ebersole +7 more
TL;DR: It is demonstrated that members of the Dehalococcoides group are widely distributed in nature and can be found in a variety of geological formations and in different climatic zones and the association of these organisms with full dechlorination of chloroethenes suggests that they are promising candidates for engineered bioremediation and may be important contributors to natural attenuation of chlorine.
Journal ArticleDOI
Rapid and sensitive pollutant detection by induction of heat shock gene-bioluminescence gene fusions.
T. K. Van Dyk,William R. Majarian,K B Konstantinov,Roslyn M. Young,Prasad Dhurjati,Robert A. LaRossa +5 more
TL;DR: Two Escherichia coli heat shock promoters, dnaK and grpE, were fused to the lux genes of Vibrio fischeri, and introduction of an outer membrane mutation, tolC, enhanced detection of a hydrophobic molecule, pentachlorophenol.
Journal ArticleDOI
Analyte detection with DNA-labeled antibodies and polymerase chain reaction.
Rolf D. Joerger,Tina M. Hatfield Truby,Edwin R. Hendrickson,Roslyn M. Young,Richard C. Ebersole +4 more
TL;DR: In this article, DNA-antibody conjugates were synthesized by using heterobifunctional cross-linker chemistries to covalently attach single or double-stranded DNA labels through amine or sulfhydryl groups on the analyte antibodies.
Journal ArticleDOI
Genetic mapping of mutations using phenotypic pools and mapped RAPD markers
TL;DR: A molecular approach to the mapping of mutant genes using RAPD markers and pooling of individuals based on phenotype is demonstrated and a mathematical model for calculating the probability of linkage between RAPDs and target genes is developed.
Analyte Detection with DNA-LabeledAntibodies and PolymeraseChain Reaction
Rolf D. Joerger,Tina M. Hatfield Truby,Edwin R. Hendrickson,Roslyn M. Young,Richard C. Ebersole +4 more
TL;DR: It is suggested that this hybrid technology could provide the basis for a new generation of ultra-sensitive immunoassays offering multianalyte capabilities.