Stereochemistry and reaction rates of anionopentaamine complexes of cobalt(III) and chromium(III)

Publisher Summary This chapter discusses recent progress in the area of kinetics and mechanisms of ligand substitution. The chapter describes classical complexes and a selection of bioinorganic reactions reflecting the growing importance of this bridging area, a few references of relevance to inorganic pharmacology, and organometallic systems. A rapidly developing area where mechanistic information is currently minimal but could usefully be greatly increased is that of self-assembly and supramolecular chemistry. The chapter focuses on catenanes, rotaxanes, helicates, and knots, to provide a qualitative view of the development of mechanistic investigation and understanding in this field. Substitution at copper(I) is an important feature of supramolecular chemistry, especially in relation to catenane formation. Mechanistic developments should be imminent in relation to the ligand-replacement reactions that are an integral part of the entry of copper into cells and of its subsequent central role in metalloprotein mediation of such processes as iron uptake and energy generation through electron transfer.

Ligand substitution reactions

Base-catalyzed solvolysis of some alkylaminepentaamminecobalt(III)complexes in ethylenediamine

Competition between ammonia and the nitrite ion as leaving groups: Hydrolysis of some nitroamminerhodium(III) complexes

Competition between ammonia and the nitrite ion as leaving groups in cobalt(III) complexes—II: Hydrolysis of the nitroamminecobalt(III) complexes in strongly alkaline media

S. Balt

Papers

Competition between ammonia and the nitrite ion as leaving groups in cobalt(III) complexes—II: Hydrolysis of the nitroamminecobalt(III) complexes in strongly alkaline media