Environment-induced decoherence and superselection have been a subject of intensive research over the past two decades, yet their implications for the foundational problems of quantum mechanics, most notably the quantum measurement problem, have remained a matter of great controversy. This paper is intended to clarify key features of the decoherence program, including its more recent results, and to investigate their application and consequences in the context of the main interpretive approaches of quantum mechanics.

http://faculty.up.edu/schlosshauer/publications/RevModPhys_76_001267.pdf

Decoherence, the measurement problem, and interpretations of quantum mechanics

Much of our understanding of human thinking is based on probabilistic models. This innovative book by Jerome R. Busemeyer and Peter D. Bruza argues that, actually, the underlying mathematical structures from quantum theory provide a much better account of human thinking than traditional models. They introduce the foundations for modelling probabilistic-dynamic systems using two aspects of quantum theory. The first, 'contextuality', is a way to understand interference effects found with inferences and decisions under conditions of uncertainty. The second, 'quantum entanglement', allows cognitive phenomena to be modeled in non-reductionist ways. Employing these principles drawn from quantum theory allows us to view human cognition and decision in a totally new light. Introducing the basic principles in an easy-to-follow way, this book does not assume a physics background or a quantum brain and comes complete with a tutorial and fully worked-out applications in important areas of cognition and decision.

/pdf/quantum-models-of-cognition-and-decision-hejlh57vgk.pdf

Quantum Models of Cognition and Decision

The nature of consciousness, the mechanism by which it occurs in the brain, and its ultimate place in the universe are unknown. We proposed in the mid 1990's that consciousness depends on biologically 'orchestrated' coherent quantum processes in collections of microtubules within brain neurons, that these quantum processes correlate with, and regulate, neuronal synaptic and membrane activity, and that the continuous Schrodinger evolution of each such process terminates in accordance with the specific Diosi-Penrose (DP) scheme of 'objective reduction' ('OR') of the quantum state. This orchestrated OR activity ('Orch OR') is taken to result in moments of conscious awareness and/or choice. The DP form of OR is related to the fundamentals of quantum mechanics and space-time geometry, so Orch OR suggests that there is a connection between the brain's biomolecular processes and the basic structure of the universe. Here we review Orch OR in light of criticisms and developments in quantum biology, neuroscience, physics and cosmology. We also introduce a novel suggestion of 'beat frequencies' of faster microtubule vibrations as a possible source of the observed electro-encephalographic ('EEG') correlates of consciousness. We conclude that consciousness plays an intrinsic role in the universe.

/pdf/consciousness-in-the-universe-fxcehocl10.pdf

Consciousness In The Universe

Neuropsychological research on the neural basis of behaviour generally posits that brain mechanisms will ultimately suffice to explain all psychologically described phenomena. This assumption stems from the idea that the brain is made up entirely of material particles and fields, and that all causal mechanisms relevant to neuroscience can therefore be formulated solely in terms of properties of these elements. Thus, terms having intrinsic mentalistic and/or experiential content (e.g. 'feeling', 'knowing' and 'effort') are not included as primary causal factors. This theoretical restriction is motivated primarily by ideas about the natural world that have been known to be fundamentally incorrect for more than three-quarters of a century. Contemporary basic physical theory differs profoundly from classic physics on the important matter of how the consciousness of human agents enters into the structure of empirical phenomena. The new principles contradict the older idea that local mechanical processes alone can account for the structure of all observed empirical data. Contemporary physical theory brings directly and irreducibly into the overall causal structure certain psychologically described choices made by human agents about how they will act. This key development in basic physical theory is applicable to neuroscience, and it provides neuroscientists and psychologists with an alternative conceptual framework for describing neural processes. Indeed, owing to certain structural features of ion channels critical to synaptic function, contemporary physical theory must in principle be used when analysing human brain dynamics. The new framework, unlike its classic-physics-based predecessor, is erected directly upon, and is compatible with, the prevailing principles of physics. It is able to represent more adequately than classic concepts the neuroplastic mechanisms relevant to the growing number of empirical studies of the capacity of directed attention and mental effort to systematically alter brain function.

/pdf/quantum-physics-in-neuroscience-and-psychology-a-9ki39mqblo.pdf

Quantum physics in neuroscience and psychology: a neurophysical model of mind–brain interaction

The hypothesis that human reasoning obeys the laws of quantum rather than classical probability has been used in recent years to explain a variety of seemingly “irrational” judgment and decision-making findings. This article provides independent evidence for this hypothesis based on an a priori prediction, called the quantum question (QQ) equality, concerning the effect of asking attitude questions successively in different orders. We empirically evaluated the predicted QQ equality using 70 national representative surveys and two laboratory experiments that manipulated question orders. Each national study contained 651–3,006 participants. The results provided strong support for the predicted QQ equality. These findings suggest that quantum probability theory, initially invented to explain noncommutativity of measurements in physics, provides a simple account for a surprising regularity regarding measurement order effects in social and behavioral science.

https://www.pnas.org/content/pnas/111/26/9431.full.pdf

Context effects produced by question orders reveal quantum nature of human judgments

The Penrose-Hameroff orchestrated objective reduction ~orch. OR! model assigns a cognitive role to quantum computations in microtubules within the neurons of the brain. Despite an apparently ‘‘warm, wet, and noisy’’ intracellular milieu, the proposal suggests that microtubules avoid environmental decoherence long enough to reach threshold for ‘‘self-collapse’’ ~objective reduction! by a quantum gravity mechanism put forth by Penrose. The model has been criticized as regards the issue of environmental decoherence, and a recent report by Tegmark finds that microtubules can maintain quantum coherence for only 10 213 s, far too short to be neurophysiologically relevant. Here, we critically examine the decoherence mechanisms likely to dominate in a biological setting and find that ~1! Tegmark’s commentary is not aimed at an existing model in the literature but rather at a hybrid that replaces the superposed protein conformations of the orch. OR theory with a soliton in superposition along the microtubule; ~2! recalculation after correcting for differences between the model on which Tegmark bases his calculations and the orch. OR model ~superposition separation, charge vs dipole, dielectric constant! lengthens the decoherence time to 10 25 ‐10 24 s; ~3! decoherence times on this order invalidate the assumptions of the derivation and determine the approximation regime considered by Tegmark to be inappropriate to the orch. OR superposition; ~4! Tegmark’s formulation yields decoherence times that increase with temperature contrary to well-established physical intuitions and the observed behavior of quantum coherent states; ~5! incoherent metabolic energy supplied to the collective dynamics ordering water in the vicinity of microtubules at a rate exceeding that of decoherence can counter decoherence effects ~in the same way that lasers avoid decoherence at room temperature!; ~6! microtubules are surrounded by a Debye layer of counterions, which can screen thermal fluctuations, and by an actin gel that might enhance the ordering of water in bundles of microtubules, further increasing the decoherence-free zone by an order of magnitude and, if the dependence on the distance between environmental ion and superposed state is accurately reflected in Tegmark’s calculation, extending decoherence times by three orders of magnitude; ~7! topological quantum computation in microtubules may be error correcting, resistant to decoherence; and ~8! the decohering effect of radiative scatterers on microtubule quantum states is negligible. These considerations bring microtubule decoherence into a regime in which quantum gravity could interact with neurophysiology.

/pdf/quantum-computation-in-brain-microtubules-decoherence-and-4y0fvi1cth.pdf

Quantum computation in brain microtubules: decoherence and biological feasibility.

The Penrose-Hameroff (`Orch OR') model of quantum computation in brain microtubules has been criticized as regards the issue of environmental decoherence. A recent report by Tegmark finds that microtubules can maintain quantum coherence for only $10^{-13}$ s, far too short to be neurophysiologically relevant. Here, we critically examine the assumptions behind Tegmark's calculation and find that: 1) Tegmark's commentary is not aimed at an existing model in the literature but rather at a hybrid that replaces the superposed protein conformations of the `Orch OR' theory with a soliton in superposition along the microtubule, 2) Tegmark predicts decreasing decoherence times at lower temperature, in direct contradiction of the observed behavior of quantum states, 3) recalculation after correcting Tegmark's equation for differences between his model and the `Orch OR' model (superposition separation, charge vs. dipole, dielectric constant) lengthens the decoherence time to $10^{-5} - 10^{-4}$ s and invalidates a critical assumption of Tegmark's derivation, 4) incoherent metabolic energy supplied to the collective dynamics ordering water in the vicinity of microtubules at a rate exceeding that of decoherence can counter decoherence effects (in the same way that lasers avoid decoherence at room temperature), and 5) phases of actin gelation may enhance the ordering of water around microtubule bundles, further increasing the decoherence-free zone by an order of magnitude and the decoherence time to $10^{-2} - 10^{-1}$ s. These revisions bring microtubule decoherence into a regime in which quantum gravity can interact with neurophysiology.

S. Hagan

Papers

Quantum computation in brain microtubules: decoherence and biological feasibility.

Quantum Computation in Brain Microtubules? Decoherence and Biological Feasibility