Showing papers by "S J Konturek published in 1973"

Effect of glucagon on food-induced gastrointestinal secretions.

Abstract: The action of glucagon on gastrointestinal secretion has been studied in two groups of 3 dogs each. The group-A dogs were prepared with gastric fistulas, Pavlov pouches and pancreatic fistulas, while the dogs in group B possessed only gastric fistulas and biliary fistulas. Glucagon infused intravenously in a dose of 25 μg/kg-h, during a steady state of half maximal secretory response to food caused a marked inhibition of acid secretion from Pavlov pouches and bicarbonate and protein secretion from pancreatic fistula. Biliary secretion was not affected by glucagon.