S.P. Lerman

TL;DR: Pretreatment of tumor recipients with macrophage inhibiting agents, such as silica, trypan blue and carrageenan, also tended to inhibit tumor growth, particularly when combined with a dose of irradiation (460 R) which by itself had only a limited effect.

TL;DR: After repeated injections of X- RCS, spleen and, to a lesser degree, lymph node cells acquired the ability to give moderate secondary cytotoxic responses in vitro upon co-culture with X-RCS, which was T-cell mediated and specific for RCS although it did not distinguish between different transplantable RCS lines.

TL;DR: Transplantable reticulum cell sarcoma fails to grow in irradiated recipients in spite of undisturbed homing characteristics and in the absence of any evidence of cytotoxic influences from the host.

TL;DR: Further examination of the phenomenon of “infectious agammaglobulinaemia” in line 6 chickens, which seems to represent an ideal laboratory model for the human disease, would be greatly facilitated by a short term assay to allow better identification of the target cell.

TL;DR: It is suggested that a difference in avidity and/or number of anti-TNP receptors per cell between virgin and primed B cells may be an important factor in determining whether the cells will be stimulated or inhibited by exposure to hapten-SIII.