Sachiko Nakamura

TL;DR: D‐K2P exhibited more potential thrombolytic effect than recombinant nt‐PA (alteplase) by both bolus and infusional administrations in the rabbit thrombus model and was also more effective in canine coronary thrombosis, which may indicate that plasma half‐life and fibrin acceleration play important roles in the thromBOlytic agent.

TL;DR: Results indicate that although labelled Tyr 270 is not essential, it does play an important role in the enzymatic activity and the inactivation by 6-BH-7ACA is due to the modification of a single residue located in the neighborhood of the substrate binding region of the acylase.

TL;DR: The results indicate that neutralizing antibodies that recognize the common epitope for several variants may be maintained for a long time, whileneutralizing antibodies having specific epitopes for a variant, produced in large quantities immediately after infection, may decrease quite rapidly.

TL;DR: It is demonstrated that at least two doses of mRNA vaccination to SARS-CoV-2 convalescent patients can induce cross-neutralizing activity against Omicron, and surprisingly and interestingly, after the second vaccination, the subject neutralizing antibody titers all became seropositive.

TL;DR: For example, CoVID-19 as mentioned in this paper was held in Shanghai, China in 2019, where 1.101% of the participants failed to pass the test.https://www.youtube.com/watchlist.php?list=watch.