Showing papers by "Saeed Bashirian published in 2023"
TL;DR: In this paper , the biomarkers of oxidative stress were evaluated in 40 workers in silica mines of Azandarian region (Hamadan province, Iran) with occupational exposure to free Crystalline Silica (CS), as the case group and 40 workers without any silica-exposure as controls.
Abstract: Introduction: In various mining activities, workers are exposed to free Crystalline Silica (CS), which can cause the constant production of reactive oxygen species and silicosis. This research was conducted to evaluate oxidative stress biomarkers and liver tissue function in workers occupationally exposed to CS during their activities.
Materials and methods: In this study, the biomarkers of oxidative stress were evaluated in 40 workers in silica mines of Azandarian region (Hamadan province, Iran) with occupational exposure to CS, as the case group and 40 workers without any silica-exposure as controls.
Results: A significant higher serum levels of Malondialdehyde (MDA), Reactive Oxygen Species (ROS) and Alanine Transaminase (ALT) were observed in the silica-exposed group compared to the controls. Moreover, in the serum of the silica-exposed cases, the total antioxidant capacity was lower than that of the control group. Based on findings chronic exposure to CS can obviously affect the serum levels of oxidative stress biomarker and liver tissue function in the exposed workers.
Conclusion: Therefore, the use of suitable face mask and different dietary antioxidants are recommended in the silica-exposed workers for the reduction of oxidative stress production and prevention of liver tissue disorders.
TL;DR: In this paper , the authors developed and evaluated the psychometric properties of the protection motivation theory questionnaire for fall prevention in older people in Iran, which is a common framework illustrating the use of protective behaviours.
Abstract: The protection motivation theory is a common framework illustrating the use of protective behaviours. The aim of this study was to develop and evaluate the psychometric properties of the protection motivation theory questionnaire for fall prevention in older people in Iran. This study used a psychometric design. A literature review was initially performed and developed a 35-item questionnaire consisting of eight sub-constructs of the protection motivation theory. A panel of experts and a group of older people aged 60 years or above were invited to assess the content and face validity of the questionnaire. Thereafter, construct validity was evaluated by using confirmatory factor analysis. The reliability of the questionnaire was examined using test–retest reliability and internal consistency. Data analysis was performed using the partial least squares path modelling version three software. A total of 300 people living in retirement centres completed the questionnaire. In the expert panel review, all tasks received a content validity index above 0.90 and a content validity ratio above 0.80, representing good content validity. In total, 32 items remained in the final version of the questionnaire. Confirmatory factor analysis confirmed an acceptable eight-factor model fit of the protection motivation theory sub-constructs with factor loadings from 0.59 to 0.93. The discriminant validity was verified using the Fornell–Larcker criterion. The Cronbach's alpha ranged from 0.68 to 0.90 and the test–retest reliability ranged from 0.78 to 0.90, displaying an acceptable result. The results of this study suggest that the protection motivation theory questionnaire had good validation and can be used to measure the psychological predictors of fall behaviour in older people. Further studies are needed to evaluate the validity in various settings.