S
Saeedah Musaed Almutairi
Researcher at University of Ottawa
Publications - 27
Citations - 156
Saeedah Musaed Almutairi is an academic researcher from University of Ottawa. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 3, co-authored 4 publications receiving 44 citations. Previous affiliations of Saeedah Musaed Almutairi include King Saud University.
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Journal ArticleDOI
Interleukin-18 up-regulates amino acid transporters and facilitates amino acid–induced mTORC1 activation in natural killer cells
Saeedah Musaed Almutairi,Saeedah Musaed Almutairi,Alaa Kassim Ali,William He,Doo-Seok Yang,Peyman Ghorbani,Lisheng Wang,Morgan D. Fullerton,Seung-Hwan Lee +8 more
TL;DR: It is demonstrated that IL-18 is a potent cytokine that can enhance the expression of the nutrient transporter CD98/LAT1 for amino acids independently of the mTORC1 pathway and thereby induce a dramatic metabolic change associated with increased proliferation of NK cells.
Journal ArticleDOI
The Prospective Effect of Allopurinol on the Oxidative Stress Index and Endothelial Dysfunction in Covid-19
Hayder M Al-Kuraishy,Ali I Al-Gareeb,Marwa S. Al-Niemi,Reem M. Aljowaie,Saeedah Musaed Almutairi,Athanasios Alexiou,Gaber El-Saber Batiha +6 more
TL;DR: In this article , the potential protective effects of allopurinol on the biomarkers of OS and ED in patients with severe Covid-19 were investigated in a single-center cohort study.
Journal ArticleDOI
Natural Killer Cell-Derived IL-10 Prevents Liver Damage During Sustained Murine Cytomegalovirus Infection.
Alaa Kassim Ali,Amandeep Kaur Komal,Saeedah Musaed Almutairi,Saeedah Musaed Almutairi,Seung-Hwan Lee +4 more
TL;DR: It is demonstrated that NK cell-derived IL-10 regulates T cell activation, prevents liver damage, and allows for better disease outcome, which can be critical in regulating the immune response during early phases of infection and therefore protecting the host from excessive immunopathology.
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Biological synthesis and characterization of passiflora subpeltata ortega aqueous leaf extract in silver nanoparticles and their evaluation of antibacterial, antioxidant, anti-cancer and larvicidal activities
Settu Loganathan,K. Selvam .,Govindaraj Padmavathi,Muthugounder Subramanian Shivakumar,Sengottayan Senthil-Nathan,Sumathi Arumuga Gounder,M. Ajmal Ali,Saeedah Musaed Almutairi +7 more
TL;DR: In this paper , green synthesis of silver nanoparticles using Passiflora subpeltata of aqueous extract (Ps-AgNPs) as reducing and stabilizing agent.
Journal Article
Reactive oxygen species modulate immune cell effector function
TL;DR: It is hypothesized that, upon stimulation of NK cells, ROS accumulate and provide positive signaling that leads to the upregulation of NK cell effector functions, and this finding will elucidate a link between the levels of ROS and immune cell proliferation during viral infection and carcinogenesis.