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Sai Ma

Researcher at College of Health Sciences, Bahrain

Publications -  5
Citations -  913

Sai Ma is an academic researcher from College of Health Sciences, Bahrain. The author has contributed to research in topics: Mitophagy & Mitochondrial fission. The author has an hindex of 4, co-authored 5 publications receiving 723 citations. Previous affiliations of Sai Ma include University of Wyoming & Fudan University.

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DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways.

Qinhua Jin, +9 more
- 01 Apr 2018 - 
TL;DR: The results of this study suggest that DUSP1 and its downstream JNK pathway are therapeutic targets for conferring protection against IR injury by repressing Mff-mediated mitochondrial fission and Bnip3-required mitophagy.
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Effects of melatonin on fatty liver disease: The role of NR4A1/DNA-PKcs/p53 pathway, mitochondrial fission, and mitophagy.

Hao Zhou, +10 more
- 01 Jan 2018 - 
TL;DR: Melatonin has the ability to cut off the NR4A1/DNA‐PKcs/p53 pathway, which confers a protective advantage to hepatocytes and mitochondria and highlights a new entry point for treating NAFLD.
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Melatonin suppresses platelet activation and function against cardiac ischemia/reperfusion injury via PPARγ/FUNDC1/mitophagy pathways

Hao Zhou, +11 more
- 01 Nov 2017 - 
TL;DR: Melatonin powerfully suppressed platelet activation via restoration of the PPARγ content in platelets, which subsequently blocked FUNDC1‐required mitophagy, mitochondrial energy production, platelet hyperactivity, and cardiac I/R injury.
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Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways.

Chen Shi, +10 more
- 01 Apr 2018 - 
TL;DR: Hippo-Yap is identified as the tumor promoter in hepatocellular carcinoma that mediated via activation of cofilin/F-actin/lamellipodium axis by limiting JNK-Bnip3-SERCA-CaMKII pathways, with potential application to HCC therapy involving cancer metastasis.
Journal Article

Abstract 16595: NAD+ Precursor Nicotinamide Riboside Alleviates Alcoholic Cardiomyopathy via Mitophagy Induction: A Novel SIRT3-PGAM5-FUNDC1 Axis

Sai Ma, +2 more
- 14 Nov 2017 - 
TL;DR: Nicotinamide riboside is widely used as a NAD+ precursor vitamin and Supplementation with NR has been shown to protect against metabolic and age-related diseases in mammals.