S
Sandra L. Phillips
Publications - 1
Citations - 393
Sandra L. Phillips is an academic researcher. The author has contributed to research in topics: Retinoid & Retinyl acetate. The author has an hindex of 1, co-authored 1 publications receiving 393 citations.
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Journal Article
N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat
Richard C. Moon,Henry J. Thompson,Peter J. Becci,Clinton J. Grubbs,Robert J. Gander,Dianne L. Newton,Joseph M. Smith,Sandra L. Phillips,William R. Henderson,Larry T. Mullen,Charles C. Brown,Michael B. Sporn +11 more
TL;DR: High-pressure liquid chromatographic analyses of liver and breast extracts from rats treated for 6 months with retinoids show the pharmacokinetic basis for the superiority of 4-hydroxyphenylretinamide; this retinoid and its metabolites were found in high concentrations in breast tissue, without any measurable accumulation in the liver or evident liver toxicity.