S
Sandra V. Verstraeten
Researcher at University of Buenos Aires
Publications - 58
Citations - 3826
Sandra V. Verstraeten is an academic researcher from University of Buenos Aires. The author has contributed to research in topics: Membrane fluidity & Liposome. The author has an hindex of 28, co-authored 56 publications receiving 3366 citations. Previous affiliations of Sandra V. Verstraeten include National Scientific and Technical Research Council.
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Basic biochemical mechanisms behind the health benefits of polyphenols.
TL;DR: A better knowledge about the nature and biological consequences of polyphenol interactions with cell components will certainly contribute to develop nutritional and pharmacological strategies oriented to prevent the onset and/or the consequences of human disease.
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Aluminium and lead: molecular mechanisms of brain toxicity
TL;DR: This review will particularly address the involvement of oxidative stress, membrane biophysics alterations, deregulation of cell signaling, and the impairment of neurotransmission as key aspects involved Al and Pb neurotoxicity.
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Flavonoid-membrane interactions: a protective role of flavonoids at the membrane surface?
Patricia I. Oteiza,Alejandra G. Erlejman,Sandra V. Verstraeten,Carl L. Keen,Cesar G. Fraga,Cesar G. Fraga +5 more
TL;DR: It is suggested that interactions of polyphenols at the surface of bilayers through hydrogen bonding, can act to reduce the access of deleterious molecules (i.e. oxidants), thus protecting the structure and function of membranes.
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The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects.
TL;DR: The hypothesis that the chemical structure of phenolics conditions their interactions with membranes, and the interactions of flavonoids with the polar head groups of phospholipids, at the lipid–water interface of membranes, should be considered among the factors that contribute to their antioxidant effects is supported.
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Flavan-3-ols and procyanidins protect liposomes against lipid oxidation and disruption of the bilayer structure.
TL;DR: Results indicate that the interaction of flavanols and procyanidins with phospholipid head groups, particularly with those containing hydroxyl groups, is associated with a reduced rate of membrane lipid oxidation.