Systematic review on herb-induced liver injury in Korea.

Systematic review of published data on herb induced liver injury.

Polygoni Multiflori Radix (PMR), Cynanchi Wilfordii Radix (CWR), and Cynanchi Auriculati Radix (CAR) are very popular herbal medicines in Traditional Korean Medicine, Traditional Chinese Medicine, and Kampo Medicine. However, the plant origins, efficacies, and traditional uses of these herbal medicines differ. In Korea, PMR is called Ha Su O (He Shou Wu in China), and CWR is called Baek Ha Su O or Baek Su O (Bai Shou Wu in China). Baek Su O refers to CWR in Korea and CAR in China. CAR has not been used as a traditional herbal medicine, and it cannot be legally used as a food or food ingredient in Korea. However, CAR is cultivated in Korea and imported from China. Because the morphology of CWR and CAR is very similar, they are often confused and misused in Korea. This review discusses the reasons for the confusion and misuse of these substances in Korea and provides the exact plant origins, efficacies, uses, components, and toxicities of PMR, CWR, and CAR so that they can be correctly understood and used.

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Discrimination and Proper Use of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea: A Descriptive Review

The desire to maintain youth and beauty has led to an increase in the use of health foods and herbs. Because Polygonum multiflorum Thunb. is thought to prevent hair loss and maintain black hair, this herb in particular has captured public interest in Korea and China. Although there have been many reports regarding the toxic effects of herbs and health foods, the potential toxicity of this herb has not yet been reported. Here, we discuss two cases of toxic hepatitis due to Polygonum multiflorum ingestion and present a review of the relevant literature.

Sang Young Han

Papers

Two cases of toxic hepatitis after Polygonum multiflorum Thunb. ingestion