S
Sanjeev Khera
Researcher at Post Graduate Institute of Medical Education and Research
Publications - 16
Citations - 90
Sanjeev Khera is an academic researcher from Post Graduate Institute of Medical Education and Research. The author has contributed to research in topics: Medicine & Leukemia. The author has an hindex of 4, co-authored 16 publications receiving 51 citations.
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Prevalence of TPMT, ITPA and NUDT 15 genetic polymorphisms and their relation to 6MP toxicity in north Indian children with acute lymphoblastic leukemia
TL;DR: Polymorphisms in ITPA and NUDT15 have a greater prevalence in the north Indian population and patients with these SNPs tolerate lower doses of 6MP, according to a comparison of groups with and without any of the studied polymorphisms.
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Emerging role of NUDT15 polymorphisms in 6-mercaptopurine metabolism and dose related toxicity in acute lymphoblastic leukaemia.
TL;DR: Current review highlights the scientific data on NUDT15 enzyme variant and its relation to 6-MP toxicity in various ethnic populations.
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Solitary serum methotrexate level 36 hours post high-dose methotrexate: A safe, efficacious, and cost-effective strategy to monitor methotrexate toxicities in childhood leukemia in resource-limited centers.
TL;DR: This work studied the efficacy and safety of “solitary 36 hours post HD‐MTX levels (MTX36),” which is to serially monitor levels till serum MTX < 0.01 μmol/L.
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Transcobalamin deficiency: vitamin B12 deficiency with normal serum B12 levels.
TL;DR: A child with TC deficiency who presented with classical clinical and lab stigmata of inborn error of vitamin B12 metabolism except normal serum B12 levels is described.
Journal Article
Safety and efficacy of azathioprine in immune thrombocytopenia.
Kundan Mishra,Suman Pramanik,Rajeev Sandal,Aditya Jandial,Kamal Kant Sahu,Kanwaljeet Singh,Sanjeev Khera,Ashok Meshram,Harshit Khurana,Venkatesan Somasundaram,Rajiv Kumar,Rajan Kapoor,Tarun Verma,Sanjeevan Sharma,Jasjit Singh,Satyaranjan Das,Tathagat Chaterjee,Ajay K. Sharma,Velu Nair +18 more
TL;DR: Azathioprine is one of the effective, readily available, and affordable immunosupressants available for ITP management in developing countries as discussed by the authors, and it is well-tolerated with minimal and manageable side effects.