An endovascular or intraluminal stent comprising an expandable framework including a plurality of interconnected undulating or otherwise connected segments, and a plurality of fibers disposed on the expandable framework. At least a portion of the plurality of fibers is loaded with a therapeutic agent.

Medical device including drug-loaded fibers

A nanocomposite structure comprising a nanostructured filler or carrier intimately mixed with a matrix, and methods of making such a structure. The nanostructured filler has a domain size sufficiently small to alter an electrical, magnetic, optical, electrochemical, chemical, thermal, biomedical, or tribological property of either filler or composite by at least 20%.

Nanostructured fillers and carriers

Nanocomposites are manufactured by combining a host material, such as an organic solvent or a matrix polymer and exfoliated intercalates formed by contacting a phyllosilicate with a polymer to adsorb or intercalate the polymer between adjacent phyllosilicate platelets. Sufficient polymer is adsorbed between adjacent phyllosilicate platelets to expand the adjacent platelets to a spacing of at least about 5 A, preferably at least about 10 A (as measured after water removal), up to about 100 A and preferably in the range of about 30-40 A, so that the intercalate easily can be exfoliated, e.g., when mixed with an organic solvent or a polymer melt, to provide a carrier material for drugs and the like, or to provide a matrix polymer/platelet composite (nanocomposite) material - the platelets being exfoliated from the intercalate.

Intercalates and exfoliates formed with oligomers and polymers and composite materials containing same

Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.

Drug delivery medical device

Graphite nanoplatelets of expanded graphite and composites and products produced therefrom are described. The preferred method of expanding the graphite is by microwaves or other radiofrequency wave treatment of intercalated graphite. The expanded graphite is preferably then crushed to nanometer (substantially all 200 microns or less). The expanded graphite is used in polymer composites. The expanded graphite is particularly useful for batteries, anodes and fuel cells.

Expanded graphite and products produced therefrom

This invention is directed to a composite formed from a gamma phase polyamide such as nylon 6 having dispersed therein a particulate material such as a phyllosilicate as for example montmorillonite.

Nanocomposites of gamma phase polymers containing inorganic particulate material

This invention is directed to a composite formed from a gamma phase polyamide such as nylon (6) having dispersed therein a particulate material such as a phyllosilicate as for example montmorillonite

Sanjeeva N. Murthy

Papers

Nanocomposites of gamma phase polymers containing inorganic particulate material

Nanocomposites of gamma phase polymers